猪殃殃酚类成分研究
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摘要
采用正相、反相硅胶柱色谱、葡聚糖凝胶柱、半制备高效液相色谱(HPLC)对猪殃殃氯仿和乙酸乙酯部位进行了化学成分的研究,分离得到了9个酚类化合物,分别为:对苯二甲酸二丁酯(1),原儿茶酸丁酯(2),原儿茶酸乙酯(3),二氢咖啡酸乙酯(4),顺式咖啡酸乙酯(5),没食子酸甲酯(6),7-羟基-6-甲氧基色酮(7),1-丙烯酸-3-(3,4-二羟苯基)戊酯(8),1-(3,4-二羟基苯)丙酮(9).这9个化合物都是首次从该属植物中分离得到.
Separation of chloroform and ethyl acetate fromGalium versicolor L.was carried out by high performance liquid chromatography(HPLC)with normal phase,reverse phase silica gel column,sephadex column and semi-preparative high performance liquid chromatography.Nine compounds were isolated,dibutyl terephthalate(1),protocatechuic acid ethyl ester(2),ethyl protocatechuate(3),dihydrocaffine ethyl ester(4),cis-caffeic acid ethyl ester(5),methyl gallate(6),7-hydroxy-6-methoxycarbonylketone(7),3-(3,4-dihydroxyphenyl)pentyl1-propenoate(8),3′,4′-dihydroxybenzene)acetone(9),all of which were isolated from this genus for the first time.
Separation of chloroform and ethyl acetate fromGalium versicolor L.was carried out by high performance liquid chromatography(HPLC)with normal phase,reverse phase silica gel column,sephadex column and semi-preparative high performance liquid chromatography.Nine compounds were isolated,dibutyl terephthalate(1),protocatechuic acid ethyl ester(2),ethyl protocatechuate(3),dihydrocaffine ethyl ester(4),cis-caffeic acid ethyl ester(5),methyl gallate(6),7-hydroxy-6-methoxycarbonylketone(7),3-(3,4-dihydroxyphenyl)pentyl1-propenoate(8),3′,4′-dihydroxybenzene)acetone(9),all of which were isolated from this genus for the first time.
引文
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[2]蔡小梅.猪殃殃化学成分的研究[D].贵州:贵州大学,2009.
[3]康文艺,王金梅,苑鹏飞.木犀属植物化学成分及药理作用研究进展[J].河南大学学报(医学版),2008,27(3):8-13.
[4]张建,杨婷婷,李国强,等.川山橙枝叶的化学成分研究[J].中国中药杂志,2013,38(10):1548-1551.
[5]KENICHI N,ATSUKO N,ISAO K.Molecular design of multifunctional food additives:antioxidative antifungal agents[J].Agricultural and Food Chemistry,2004,52(16):5011-5020.
[6]李静,徐康平,邹辉,等.胡桃楸青果皮及化学成分研究[J].中南药学,2013,11(1):1-3.
[7]孟艳辉,邓芹英,许国溪.黄草的化学成分研究II[J].天然产物研究与开发,2000,12(3):27.
[8]高俊峰,丁玲,张鹏,等.石见穿化学成分研究[J].中国中药杂志,2013,38(10):1556-1559.
[9]ZHANG Y,CHEN Y,LIN X,et al.A new inositol derivative from Prenanthes macrophylla[J].Asian Natural Products Research,2012,14(2):182-185.
[10]刘杰,李国强,吴霞,等.连钱草的化学成分研究[J].中国中药杂志,2014,39(4):695-698.
[11]MERAGELMAN T L,RENTERIA B S,SILVA G L,et al.Modified secoiridoid from Acicarpha tribuloides and inhibition of nitric oxide production in LPS-activated macrophages[J].Phytochemistry,2006,67(14):1534-1538.
[12]DEEPAK D,KHARE M P,KHARE A.A pregnane ester glycoside from Periploca calophylla[J].Phytochemistry,1985,24(5):1037-1039.
[13]ZHU Y,ZHANG LX,ZHAO Y,et al.Unusual sesquiterpene lactones with a new carbon skeleton and new acetylenes from ajania przewalskii[J].Food Chem,2010,118(2):228-238.
[14]李娟,何峰,尹娴,等.土贝母正丁醇部位化学成分研究[J].华中师范大学学报(自然科学版),2016,50(5):721-725.