甲维盐高效氯氰菊酯水分散细粒剂的制备及质量评价
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摘要
[目的]制备甲维盐高效氯氰菊酯水分散细粒剂,并优化其制备工艺。[方法]以泊洛沙姆188为黏合剂,采用熔融法制备了甲维盐高效氯氰菊酯水分散细粒剂,并以悬浮率为评价指标,通过正交试验设计对制备工艺进行优化。[结果]熔融法制备甲维盐高效氯氰菊酯水分散细粒剂的最佳制备工艺为甲维盐与高效氯氰菊酯比例为1∶9,泊洛沙姆188的用量为20%,十二烷基硫酸钠的用量为1%,泊洛沙姆的活化温度为80℃。[结论]甲维盐高效氯氰菊酯细粒剂的制备工艺可行,制剂悬浮率为98.74%,符合农药制剂的质量标准。
[Aims] Emamectin benzoate cypermethrin water dispersible granules was prepared, and the process was optimized. [Methods] Emamectin benzoate cypermethrin water dispersible granules was prepared with poloxamer 188 as adhesive by melt method. The preparation process was optimized by orthogonal experiment design with suspension rate as evaluation index. [Results] The optimum process for preparation of emamectin benzoate cypermethrin water dispersible granules was: the mass ratio of emamectin benzoate to cypermethrin was 1:9, the dosages of poloxamer 188 and sodium dodecyl sulfate were 20 and 1%, respectively, the activation temperature was 80 ℃. [Conclusions] The process for the preparation of emamectin benzoate cypermethrin water dispersion fine granules was 98.74%, which meets the quality standards of pesticide formulations.
[Aims] Emamectin benzoate cypermethrin water dispersible granules was prepared, and the process was optimized. [Methods] Emamectin benzoate cypermethrin water dispersible granules was prepared with poloxamer 188 as adhesive by melt method. The preparation process was optimized by orthogonal experiment design with suspension rate as evaluation index. [Results] The optimum process for preparation of emamectin benzoate cypermethrin water dispersible granules was: the mass ratio of emamectin benzoate to cypermethrin was 1:9, the dosages of poloxamer 188 and sodium dodecyl sulfate were 20 and 1%, respectively, the activation temperature was 80 ℃. [Conclusions] The process for the preparation of emamectin benzoate cypermethrin water dispersion fine granules was 98.74%, which meets the quality standards of pesticide formulations.
引文
[1]王龙龙,刘钰,崔蕊蕊,等.甲氨基阿维菌素苯甲酸盐研究开发现状与展望[J].农药,2015,54(6):394-398.
[2]徐晓辉,吴书平,马秀玲.农药的发展与使用综述[J].安徽农学通报,2014,20(11):1.
[3]田雪玲.农药对生态环境的污染与防治[J].现代农业科技,2013,24(8):248.
[4]袁传卫,姜兴印.浅谈农药剂型的研究现状[J].世界农药,2013,35(5):54-58.
[5]徐红霞.农药科学混配技术探究[J].农技服务,2015,32(4):113-114.
[6]武德兰,周同新.农药的科学合理使用技术[J].宿州教育学院学报,2011,14(6):152-154.
[7]李翠英.农药混用的几个原则[J].新农村,2013,8(2):29-30.
[8]ALAN K,商建.安全农药剂型和农药助剂的发展趋势[J].世界农药,2011,33(4):52-56.
[9]杨益军.我国农药制剂产业的现状特点及发展方向[J].农药市场信息,2014,50(4):39-53.
[10]张保华,杨利,王智.苯醚甲环唑-多菌灵水悬浮剂配方的研究与开发[J].浙江农业科学,2011,48(5):1105-1109.
[11]中华人民共和国农业部农药检定所.农药登记公告汇编[M].北京:中国农业大学出版社,2007.
[12]凌世海.农药剂型加工丛书固体制剂[M].3版.北京:化学工业出版社,2003:439-468.
[2]徐晓辉,吴书平,马秀玲.农药的发展与使用综述[J].安徽农学通报,2014,20(11):1.
[3]田雪玲.农药对生态环境的污染与防治[J].现代农业科技,2013,24(8):248.
[4]袁传卫,姜兴印.浅谈农药剂型的研究现状[J].世界农药,2013,35(5):54-58.
[5]徐红霞.农药科学混配技术探究[J].农技服务,2015,32(4):113-114.
[6]武德兰,周同新.农药的科学合理使用技术[J].宿州教育学院学报,2011,14(6):152-154.
[7]李翠英.农药混用的几个原则[J].新农村,2013,8(2):29-30.
[8]ALAN K,商建.安全农药剂型和农药助剂的发展趋势[J].世界农药,2011,33(4):52-56.
[9]杨益军.我国农药制剂产业的现状特点及发展方向[J].农药市场信息,2014,50(4):39-53.
[10]张保华,杨利,王智.苯醚甲环唑-多菌灵水悬浮剂配方的研究与开发[J].浙江农业科学,2011,48(5):1105-1109.
[11]中华人民共和国农业部农药检定所.农药登记公告汇编[M].北京:中国农业大学出版社,2007.
[12]凌世海.农药剂型加工丛书固体制剂[M].3版.北京:化学工业出版社,2003:439-468.