南昌市2017年百日咳流行病学分析及干预措施探讨
|
摘要
目的了解南昌市2017年百日咳流行特点及近年流行规律,探讨百日咳发病控制策略及干预措施。方法采用描述流行病学方法对南昌市2017年百日咳疫情资料进行分析。结果南昌市2017年共报告百日咳病例75例; 10个县区有病例发生,以散居儿童为主,其次为学生、幼托儿童。全年均有发病,8～9月报告较多;发病主要集中在6岁以下年龄组。结论应进一步加强百日咳监测,做好百日咳疫情调查与处置,并关注小月龄婴儿在百日咳疫情传播中的作用,对百日咳发病高风险人群采取宣教、疫苗接种等措施,降低发病率。
Objective To study the epidemic characteristics of pertussis in Nanchang City in 2017 and the epidemic regularity in recent years,and to explore the control strategy and intervention measures of pertussis. Methods The descriptive epidemiologic method was used to analyze the data of pertussis in Nanchang City in 2017. Results In 2017,Nanchang City has reported 75 cases of pertussis; 10 cases occurred in the county,mainly scattered children,followed by students and children. There were onset in the whole year,and the cases were mainly concentrated in August and September. The incidence was mainly concentrated in the age group of those under 6 years old. Conclusion It' s necessary to further strengthen the monitoring of pertussis,investigate and deal with pertussis epidemics,and pay attention to the role of the infants in the spread of pertussis,and adopt measures such as education and vaccination for people at high risk of pertussis to reduce the incidence.
Objective To study the epidemic characteristics of pertussis in Nanchang City in 2017 and the epidemic regularity in recent years,and to explore the control strategy and intervention measures of pertussis. Methods The descriptive epidemiologic method was used to analyze the data of pertussis in Nanchang City in 2017. Results In 2017,Nanchang City has reported 75 cases of pertussis; 10 cases occurred in the county,mainly scattered children,followed by students and children. There were onset in the whole year,and the cases were mainly concentrated in August and September. The incidence was mainly concentrated in the age group of those under 6 years old. Conclusion It' s necessary to further strengthen the monitoring of pertussis,investigate and deal with pertussis epidemics,and pay attention to the role of the infants in the spread of pertussis,and adopt measures such as education and vaccination for people at high risk of pertussis to reduce the incidence.
引文
[1]彭文伟.传染病学[M]. 6版.北京:人民卫生出版社,2004:164-165.
[2]蒋凤,张德著,张丽,等. 2004-2015年贵州省遵义市百日咳报告病例的流行病学特征分析[J].现代预防医学,2017,44(16):2909-2911,2967.
[3]谭斌,李娟,喻林玲,等.重庆市渝北区2005-2015年百日咳流行病学特征分析[J].医学动物防制,2016,32(11):1214-1218.
[4]高志刚,黄海涛,刘勇,等.天津市百日咳发病反弹及流行病学特征改变的影响因素分析[J].中国疫苗和免疫,2011,17(3):212-215.
[5]黄海涛,高志刚,刘勇,等.天津市百日咳家庭内传播的流行特征及其影响因素[J].职业与健康,2014,30(23):3468-3472.
[6]卫辰,王丽婵,晁哲,等. 2012-2016年组分百日咳疫苗质量趋势分析及评价[J].中国生物制品学杂志,2018,31(3):225-229,235.
[7] OHFUJI S,OKADA K,NAKANO T,et al. Effectiveness of acellular pertussis vaccine in a routine immunization program:a multicenter,casecontrol study in Japan[J]. Vaccine,2015,33(8):1027-1032.
[8]王静敏,李洁,袁林,等. 0~15岁健康人群及产妇血清百日咳抗体水平的检测[J].中国疫苗和免疫,2002,8(3):141-143.
[9] HALLANDER HO,GUSTAFSSON L,LJUNGMAN M,et al. Pertussis antitoxin decay after vaccination with DTPa. Response to afirst booster dose3 1/2-6 1/2 years after the third vaccine dose[J]. Vaccine,2005,23(46/47):5359-5364.
[10] GUSTAFSSON L,HESSEL L,STORSAETER J,et al. Long-term follow-up of Swedish children vaccinated with acellular pertussis vaccines at 3,5,and 12 months of age indicates the need for a booster dose at 5to 7 years of age[J]. Pediatrics,2006,118(3):978-984.
[11]宁桂军,吴丹,李军宏,等.全球2010-2014年白喉、破伤风和百日咳免疫预防和发病水平现况分析[J].中国疫苗和免疫,2016,22(2):159-164.
[12]刁连东,徐爱强.百日咳免疫预防专家共识[J].中华流行病学杂志,2011,32(6):550-553.
[13]赵玉芹,涂秋凤,程慧健,等. 2015年江西省国家免疫规划疫苗接种率调查结果分析[J].现代预防医学,2016,43(21):4009-4014.
[14] JUSTENHOVEN C,HAMANN U,PESCH B,et al. ERCC2 genotypes and a corresponding haplotype are linked with breast cancer risk in a German population[J]. Cancer Epidemiology Biomarkers&Prevention,2004,13(12):2059-2064.
[15]姚宁,王青,周春碚. 2015年重庆市健康人群百日咳抗体水平特征分析[J].疾病监测,2017,32(6):490-493.
[16]张颖,黄海涛,刘勇,等.天津市社区人群百日咳发病监测及传播特征研究[J].中国疫苗和免疫,2011,17(3):209-211.
[2]蒋凤,张德著,张丽,等. 2004-2015年贵州省遵义市百日咳报告病例的流行病学特征分析[J].现代预防医学,2017,44(16):2909-2911,2967.
[3]谭斌,李娟,喻林玲,等.重庆市渝北区2005-2015年百日咳流行病学特征分析[J].医学动物防制,2016,32(11):1214-1218.
[4]高志刚,黄海涛,刘勇,等.天津市百日咳发病反弹及流行病学特征改变的影响因素分析[J].中国疫苗和免疫,2011,17(3):212-215.
[5]黄海涛,高志刚,刘勇,等.天津市百日咳家庭内传播的流行特征及其影响因素[J].职业与健康,2014,30(23):3468-3472.
[6]卫辰,王丽婵,晁哲,等. 2012-2016年组分百日咳疫苗质量趋势分析及评价[J].中国生物制品学杂志,2018,31(3):225-229,235.
[7] OHFUJI S,OKADA K,NAKANO T,et al. Effectiveness of acellular pertussis vaccine in a routine immunization program:a multicenter,casecontrol study in Japan[J]. Vaccine,2015,33(8):1027-1032.
[8]王静敏,李洁,袁林,等. 0~15岁健康人群及产妇血清百日咳抗体水平的检测[J].中国疫苗和免疫,2002,8(3):141-143.
[9] HALLANDER HO,GUSTAFSSON L,LJUNGMAN M,et al. Pertussis antitoxin decay after vaccination with DTPa. Response to afirst booster dose3 1/2-6 1/2 years after the third vaccine dose[J]. Vaccine,2005,23(46/47):5359-5364.
[10] GUSTAFSSON L,HESSEL L,STORSAETER J,et al. Long-term follow-up of Swedish children vaccinated with acellular pertussis vaccines at 3,5,and 12 months of age indicates the need for a booster dose at 5to 7 years of age[J]. Pediatrics,2006,118(3):978-984.
[11]宁桂军,吴丹,李军宏,等.全球2010-2014年白喉、破伤风和百日咳免疫预防和发病水平现况分析[J].中国疫苗和免疫,2016,22(2):159-164.
[12]刁连东,徐爱强.百日咳免疫预防专家共识[J].中华流行病学杂志,2011,32(6):550-553.
[13]赵玉芹,涂秋凤,程慧健,等. 2015年江西省国家免疫规划疫苗接种率调查结果分析[J].现代预防医学,2016,43(21):4009-4014.
[14] JUSTENHOVEN C,HAMANN U,PESCH B,et al. ERCC2 genotypes and a corresponding haplotype are linked with breast cancer risk in a German population[J]. Cancer Epidemiology Biomarkers&Prevention,2004,13(12):2059-2064.
[15]姚宁,王青,周春碚. 2015年重庆市健康人群百日咳抗体水平特征分析[J].疾病监测,2017,32(6):490-493.
[16]张颖,黄海涛,刘勇,等.天津市社区人群百日咳发病监测及传播特征研究[J].中国疫苗和免疫,2011,17(3):209-211.