伴抑郁症状精神分裂症采用齐拉西酮及心理治疗临床疗效分析
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摘要
目的:研究伴抑郁症状精神分裂症采用齐拉西酮及心理治疗的临床疗效。方法:本次研究选取的研究对象为2016年12月—2018年2月在我院进行治疗的伴抑郁症状精神分裂症患者,将96例患者按照就诊时间分为两组,48例每组。单月就诊为对照组(单用齐拉西酮),双月就诊为观察组(给予齐拉西酮配合心理治疗)。将两组的临床效果、PANSS量表评分、抑郁评分、不良反应发生情况进行比对。结果:观察组伴抑郁症状精神分裂症患者治疗后的PANSS量表总分、抑郁评分和不良反应发生率均低于对照组(P <0.05),临床总有效率显著更高(P <0.05)。结论:齐拉西酮联合心理治疗伴抑郁症状精神分裂症患者的效果安全有效。
Objective: To observe clinical effects of ziprasidone and psychotherapy on schizophrenia with depressive symptoms.Methods: 96 patients with schizophrenia with depressive symptoms were divided into the observation group and the control group by arrival time, 48 cases in each. The control group was treated with ziprasidone in odd month. The observation group was treated by psychotherapy more in even month. Results: After treatment, scale PANSS total score, depression score and adverse effect incidence rate in the observation group were lower than those in the control group(P<0.05). The total efficiency rate in the observation group was higher than that in the control group(P<0.05). Conclusion: Ziprasidone and psychotherapy on schizophrenia with depressive symptoms is effective and safe.
Objective: To observe clinical effects of ziprasidone and psychotherapy on schizophrenia with depressive symptoms.Methods: 96 patients with schizophrenia with depressive symptoms were divided into the observation group and the control group by arrival time, 48 cases in each. The control group was treated with ziprasidone in odd month. The observation group was treated by psychotherapy more in even month. Results: After treatment, scale PANSS total score, depression score and adverse effect incidence rate in the observation group were lower than those in the control group(P<0.05). The total efficiency rate in the observation group was higher than that in the control group(P<0.05). Conclusion: Ziprasidone and psychotherapy on schizophrenia with depressive symptoms is effective and safe.
引文
[1]王延祜,穆朝娟,刘兰芬.齐拉西酮及心理治疗对伴抑郁症状精神分裂症的临床研究[J].精神医学杂志,2015,28(6):433-436.
[2]张红燕,侯萍,时淑芳.齐拉西酮配合心理治疗用于精神分裂症抑郁症状疗效分析[J].中国现代医药杂志,2015,17(8):87-88.
[3]刘期文.齐拉西酮配合心理治疗抑郁症状精神分裂症69例的观察[J].贵阳中医学院学报,2013,35(3):109-111.
[4]乔建国.齐拉西酮及心理治疗对伴抑郁症状精神分裂症患者的临床效果研究[J].中国实用医药,2016,11(19):177-178.
[5]万晓娜,李桂臣.齐拉西酮治疗精神分裂症伴抑郁症状患者的临床疗效[J].中国现代医生,2017,55(6):100-102.
[6]易伟.齐拉西酮联用艾司西酞普兰治疗伴发抑郁症状精神分裂患者疗效及安全性分析[J].临床合理用药杂志,2016,9(17):36-37.
[7]蔡丽莉,李立群,李洋,等.齐拉西酮与利培酮对精神分裂症伴抑郁患者疗效及代谢功能的影响[J].临床心身疾病杂志,2016,22(4):23-25.
[8]吴恩辉,杨致蓉,黄宁宁.齐拉西酮及心理治疗对精神分裂症伴抑郁症状患者的疗效观察[J].中国现代医生,2017,55(3):73-75.
[2]张红燕,侯萍,时淑芳.齐拉西酮配合心理治疗用于精神分裂症抑郁症状疗效分析[J].中国现代医药杂志,2015,17(8):87-88.
[3]刘期文.齐拉西酮配合心理治疗抑郁症状精神分裂症69例的观察[J].贵阳中医学院学报,2013,35(3):109-111.
[4]乔建国.齐拉西酮及心理治疗对伴抑郁症状精神分裂症患者的临床效果研究[J].中国实用医药,2016,11(19):177-178.
[5]万晓娜,李桂臣.齐拉西酮治疗精神分裂症伴抑郁症状患者的临床疗效[J].中国现代医生,2017,55(6):100-102.
[6]易伟.齐拉西酮联用艾司西酞普兰治疗伴发抑郁症状精神分裂患者疗效及安全性分析[J].临床合理用药杂志,2016,9(17):36-37.
[7]蔡丽莉,李立群,李洋,等.齐拉西酮与利培酮对精神分裂症伴抑郁患者疗效及代谢功能的影响[J].临床心身疾病杂志,2016,22(4):23-25.
[8]吴恩辉,杨致蓉,黄宁宁.齐拉西酮及心理治疗对精神分裂症伴抑郁症状患者的疗效观察[J].中国现代医生,2017,55(3):73-75.