邵念方教授治疗胸痹心痛用药规律分析
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摘要
目的:基于中医传承辅助平台软件,挖掘邵念方教授治疗胸痹心痛的用药经验。方法:收集邵念方教授治疗胸痹心痛的门诊病例,采用熵聚类等无监督数据挖掘技术,确定药物的四气、五味、归经及药物频次和用量,分析邵念方教授治疗胸痹心痛的用药经验。结果:对筛选出的118首方剂进行分析,涉及中药160味,确定处方中药物的使用频次及药物的常规用量,挖掘出3个核心组合和3个潜在药物新组合。结论:邵念方教授治疗胸痹经验多用健脾消食、活血祛瘀止痛、益气滋阴、化痰开窍、安神定志、生津止渴、降压之品。治疗以益气活血为根本治疗大法。
Objective: To excavate Professor Shao Nianfang's medication experience in treating chest pain and heartache based on the TCM heritage supporting platform software. Methods: Professor Shao Nianfang' s outpatient cases for chest Bi and heartache were collected. Unsupervised data mining techniques such as entropy clustering were used to determine the four natures of drugs,five flavors,meridian tropism and drug frequency and dosage of the drug,and analyzed professor Shao Nianfang's medication experience in treating chest Bi and heartache. Results: The selected 118 prescriptions were analyzed,involving 160 flavors of Chinese medicine,determined the frequency of use of the drugs in the prescription and the conventional dosage of the drugs,and excavated three core combinations and three new potential combinations of potential drugs. Conclusion: Professor Shao Nianfang's experience in treating chest Bi often uses strengthening spleen and digestion,promoting blood circulation and relieving pain,replenishing qi and nourishing yin,resolving phlegm and inducing resuscitation,calming the nerves,promoting the production of body fluid and quenching thirst and reducing blood pressure. Benefiting qi and promoting blood circulation is the basic therapeutic method.
Objective: To excavate Professor Shao Nianfang's medication experience in treating chest pain and heartache based on the TCM heritage supporting platform software. Methods: Professor Shao Nianfang' s outpatient cases for chest Bi and heartache were collected. Unsupervised data mining techniques such as entropy clustering were used to determine the four natures of drugs,five flavors,meridian tropism and drug frequency and dosage of the drug,and analyzed professor Shao Nianfang's medication experience in treating chest Bi and heartache. Results: The selected 118 prescriptions were analyzed,involving 160 flavors of Chinese medicine,determined the frequency of use of the drugs in the prescription and the conventional dosage of the drugs,and excavated three core combinations and three new potential combinations of potential drugs. Conclusion: Professor Shao Nianfang's experience in treating chest Bi often uses strengthening spleen and digestion,promoting blood circulation and relieving pain,replenishing qi and nourishing yin,resolving phlegm and inducing resuscitation,calming the nerves,promoting the production of body fluid and quenching thirst and reducing blood pressure. Benefiting qi and promoting blood circulation is the basic therapeutic method.
引文
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[13]王俊霞,年莉,周志焕.古代胸痹心痛方剂配伍规律研究[J].中医学报,2014,29(4):610-611.
[14]侯养彪,林寓淞,张再良.《金匮要略》病名特点及其规范[J].中医学报,2016,31(3):379-381.
[15]吴智春,季旭明,于华芸,等.基于中医传承辅助系统的治疗老年高血压组方规律分析[J].世界中西医结合杂志,2013,8(7):649-650.
[2]庄贺,侯王君,庄慧魁,等.邵念方教授益气活血法治疗冠心病医案2则[J].中医药导报,2014,20(7):150.
[3]陈修保,陈维达,刘秀娟,等.邵念方教授补气饮治疗老年气虚血瘀型胸痹经验[J].中医临床研究,2013,5(9):68-70.
[4]赵艳青,滕晶,杨洪军.基于数据挖掘的现代中医药治疗抑郁症用药规律分析[J].中华中医药杂志,2015,40(10):2042-2046.
[5]赵艳青,滕晶.基于中医传承辅助平台的胁痛治疗方剂组方用药规律分析[J].中国中药杂志,2015,40(6):1203-1206.
[6]庄贺,侯王君.基于中医传承辅助平台的慢性阻塞性肺疾病治疗方剂组方规律分析[J].时珍国医国药,2016,27(7):1785-1787.
[7]侯王君,庄贺,薛一涛,等.基于中医传承辅助平台的薛一涛教授治疗冠心病的方剂组方规律分析[J].时珍国医国药,2016,27(10):2508-2510.
[8]吴嘉瑞,郭位先,黄秀勤,等.基于数据挖掘的孟河名医马培之治疗咯血用药规律研究[J].中国中药杂志,2014,39(4):627.
[9]庄贺,侯王君,庄慧魁,等.茂参益气滴丸联合西药治疗冠状动脉粥样硬化性心脏病心绞痛临床研究[J].河南中医,2013,33(12):2104-2105.
[10]周启东.中西医结合治疗冠心病心绞痛临床研究[J].中医学报,2010,25(4):733-735.
[11]薛一涛,潘延飞.扩张型心肌病中西医治疗进展[J].山东中医杂志,2002,21(10):634-636.
[12]江磊磊,梅晓云.胸痹心痛病因病机研究述评[J].中医学报,2012,27(2):178-180.
[13]王俊霞,年莉,周志焕.古代胸痹心痛方剂配伍规律研究[J].中医学报,2014,29(4):610-611.
[14]侯养彪,林寓淞,张再良.《金匮要略》病名特点及其规范[J].中医学报,2016,31(3):379-381.
[15]吴智春,季旭明,于华芸,等.基于中医传承辅助系统的治疗老年高血压组方规律分析[J].世界中西医结合杂志,2013,8(7):649-650.