成都市成年人夜间睡眠时长、午间睡眠时长与代谢综合征的关系
|
摘要
目的明确成都市各年龄段成年人代谢综合征(metabolic syndrome, MS)与睡眠时长的关系。方法采用随机整群抽样法收集成都市1 274名20～70岁居民为研究对象,分为青年、中年和老年三组。午睡时长由公式(平均午睡时长×午睡频率/7)获得。夜晚睡眠时长通过问题"你每天晚上平均睡眠时间是多久"获得。MS采用国际糖尿病联盟的诊断标准。结果青年组、中年组和老年组MS的患病率分别为13.8%,36.4%,40.7%(P<0.001)。在调整了混杂因素后,中年组中午睡时长在1 h内相对于无午睡习惯的人,血压(BP)和空腹血糖(FPG)升高的OR值为0.64(0.42, 0.96),0.60(0.40, 0.90),而午睡时长>1 h与MS的发生风险无关。夜间睡眠时长<6 h相对于6～8 h的人,发生MS,中心性肥胖的OR值分别为1.81(1.16, 2.82),1.67(1.05, 2.70),而夜间睡眠时长>8 h与MS的发生风险无关。青年组和老年组中,均没有发现午睡时长、夜间睡眠时长与MS的关联。结论成都市成年人MS患病率随年龄增加而逐渐增高。45～59岁成年人中,夜间睡眠时长<6 h患MS和中心性肥胖的风险可能高于6～8 h的,午睡时长在1 h以内患BP升高和FPG升高的风险可能低于无午睡的人。
Objective The aim of this study was to examine whether sleep duration is related to MS among adults in Chengdu.Methods A total of 1,274 adults aged 20-70 years were randomly selected. The nocturnal sleep duration(NSD) was determined according to the answer to the question, "On average, how long do you usually sleep per night?" The nap time of subjects were collected according to the answer by the question, "How many days do you have a nap in a week and how long do you sleep for a nap?" International Diabetes Federation defined MS according to the criterion. Results The incidence rate of MS in young, middle-aged and elder adults were approximately 13.8%, 36.4% and 40.7%, respectively. After adjustment for potential confounders, OR(95% CI) of NSD <6 hours group was significantly associated with an increased risk of MS, central obesity among middle-aged adults OR: 1.81(1.16, 2.82), 1.67(1.05, 2.70). Napped <1 hour was significantly associated with a decreased risk of raised BP and raised FPG among middle-aged adults OR: 0.64(0.42, 0.92), 0.60(0.40, 0.90). Conclusion The prevalence of MS increased with age. Individuals with short NSD had higher risk of MS, and appropriate daytime napping was associated with a decreased prevalence of raised BP and raised FPG among middle-aged adults in Chengdu.
Objective The aim of this study was to examine whether sleep duration is related to MS among adults in Chengdu.Methods A total of 1,274 adults aged 20-70 years were randomly selected. The nocturnal sleep duration(NSD) was determined according to the answer to the question, "On average, how long do you usually sleep per night?" The nap time of subjects were collected according to the answer by the question, "How many days do you have a nap in a week and how long do you sleep for a nap?" International Diabetes Federation defined MS according to the criterion. Results The incidence rate of MS in young, middle-aged and elder adults were approximately 13.8%, 36.4% and 40.7%, respectively. After adjustment for potential confounders, OR(95% CI) of NSD <6 hours group was significantly associated with an increased risk of MS, central obesity among middle-aged adults OR: 1.81(1.16, 2.82), 1.67(1.05, 2.70). Napped <1 hour was significantly associated with a decreased risk of raised BP and raised FPG among middle-aged adults OR: 0.64(0.42, 0.92), 0.60(0.40, 0.90). Conclusion The prevalence of MS increased with age. Individuals with short NSD had higher risk of MS, and appropriate daytime napping was associated with a decreased prevalence of raised BP and raised FPG among middle-aged adults in Chengdu.
引文
[1]何宇纳,赵文华,赵丽云,等.中国2010-2012年成年人代谢综合征流行特征[J].中华流行病学杂志,2017,38(2):212-215.
[2]Xi B,He D,Zhang M,et al.Short sleep duration predicts risk of metabolic syndrome:a systematic review and meta-analysis[J].Sleep Medicine Reviews,2014,18(4):293-297.
[3]廖建桥,许群珍,袁子云,等.午睡在中国的流行性及原因分析[J].人类工效学,2000,6(2):16-19,70.
[4]Yu D,Zhang X,Xiang YB,et al.Adherence to dietary guidelines and mortality:a report from prospective cohort studies of 134,000 Chinese adults in urban Shanghai[J].American Journal of Clinical Nutrition,2014,100(2):693-700.
[5]Xue H,Yang M,Liu Y,et al.Relative validity of a 2‐day 24‐hour dietary recall compared with a 2‐day weighed dietary record among adults in South China[J].Nutrition and Dietetics,2017,74(3):298-307.
[6]Ainsworth BE,Haskell WL,Herrmann SD,et al.2011 compendium of physical activities:a second update of codes and Met values[J].Medicine and Science in Sports and Exercise,2011,43(8):1575-1581.
[7]Lin DZ,Sun K,Li F,et al.Association between habitual daytime napping and metabolic syndrome:a population-based study[J].Metabolism-Clinical and Experimental,2014,63(12):1520-1527.
[8]Wu MC,Yang YC,Wu JS,et al.Short sleep duration associated with a higher prevalence of metabolic syndrome in an apparently healthy population[J].Preventive Medicine,2012,55(4):305-309.
[9]Alberti G,Zimmet P,Shaw J,et al.The IDF consensus worldwide definition of the metabolic syndrome[EB/OL].[2019-03-20].https://www.idf.org/e-library/consen sus-statements/60-idfconsensus-worldwide-definitionof-the-metabolic-syndrome.html.
[10]Ford ES,Li CY,Wheaton AG,et al.Sleep duration and body mass index and waist circumference among US adults[J].Obesity,2014,22(2):598-607.
[11]Taheri S,Lin L,Austin D,et al.Short sleep duration is associated with reduced leptin,elevated ghrelin,and increased body mass index[J].PLOS Medicine,2004,1(3):e62.
[12]Chaput JP,Mcneil J,Despres J,et al.Short sleep duration as a risk factor for the development of the metabolic syndrome in adults[J].Preventive Medicine,2013,57(6):872-877.
[13]Ervin RB.Prevalence of metabolic syndrome among adults 20 years of age and over,by sex,age,race and ethnicity,and body mass index:United States,2003-2006[J].National Health Statistics Reports,2009,5(13):1-7.
[14]胡宾,周玉杰.代谢综合征发病机制的研究进展[J].中华老年心脑血管病杂志,2012,14(3):336-337.
[15]高霞,张菊英,王敏,等.四川省城市居民慢性病患病率及影响因素分析[J].现代预防医学,2007,34(20):3821-3822,3827.
[16]Stefani KM,Kim HC,Kim J,et al.The influence of sex and age on the relationship between sleep duration and metabolic syndrome in Korean adults[J].Diabetes Research and Clinical Practice,2013,102(3):250-259.
[17]孙训明,胡淑娟,姚舜,等.午睡与高血压的相关性[J].中华高血压杂志,2016(4):329-333.
[18]李志强,吴东妮,肖艳杰,等.睡眠与2型糖尿病关系的病例对照研究[J].现代预防医学,2012,39(19):5046-5047,5051.
[19]Shan ZL,Ma HF,Xie ML,et al.Sleep duration and risk of type 2 diabetes:a meta-analysis of prospective studies[J].Diabetes Care,2015,38(3):529-537.
[20]Fang J,Wheaton AG,Keenan NL,et al.Association of sleep duration and hypertension among US adults varies by age and sex[J].American Journal of Hypertension,2012,25(3):335-341.
[21]Cao Z,Shen L,Wu J,et al.The effects of midday nap duration on the risk of hypertension in a middle-aged and older Chinese population:a preliminary evidence from the Tongji-Dongfeng Cohort Study,China[J].Journal of Hypertension,2014,32(10):1993-1998.
[2]Xi B,He D,Zhang M,et al.Short sleep duration predicts risk of metabolic syndrome:a systematic review and meta-analysis[J].Sleep Medicine Reviews,2014,18(4):293-297.
[3]廖建桥,许群珍,袁子云,等.午睡在中国的流行性及原因分析[J].人类工效学,2000,6(2):16-19,70.
[4]Yu D,Zhang X,Xiang YB,et al.Adherence to dietary guidelines and mortality:a report from prospective cohort studies of 134,000 Chinese adults in urban Shanghai[J].American Journal of Clinical Nutrition,2014,100(2):693-700.
[5]Xue H,Yang M,Liu Y,et al.Relative validity of a 2‐day 24‐hour dietary recall compared with a 2‐day weighed dietary record among adults in South China[J].Nutrition and Dietetics,2017,74(3):298-307.
[6]Ainsworth BE,Haskell WL,Herrmann SD,et al.2011 compendium of physical activities:a second update of codes and Met values[J].Medicine and Science in Sports and Exercise,2011,43(8):1575-1581.
[7]Lin DZ,Sun K,Li F,et al.Association between habitual daytime napping and metabolic syndrome:a population-based study[J].Metabolism-Clinical and Experimental,2014,63(12):1520-1527.
[8]Wu MC,Yang YC,Wu JS,et al.Short sleep duration associated with a higher prevalence of metabolic syndrome in an apparently healthy population[J].Preventive Medicine,2012,55(4):305-309.
[9]Alberti G,Zimmet P,Shaw J,et al.The IDF consensus worldwide definition of the metabolic syndrome[EB/OL].[2019-03-20].https://www.idf.org/e-library/consen sus-statements/60-idfconsensus-worldwide-definitionof-the-metabolic-syndrome.html.
[10]Ford ES,Li CY,Wheaton AG,et al.Sleep duration and body mass index and waist circumference among US adults[J].Obesity,2014,22(2):598-607.
[11]Taheri S,Lin L,Austin D,et al.Short sleep duration is associated with reduced leptin,elevated ghrelin,and increased body mass index[J].PLOS Medicine,2004,1(3):e62.
[12]Chaput JP,Mcneil J,Despres J,et al.Short sleep duration as a risk factor for the development of the metabolic syndrome in adults[J].Preventive Medicine,2013,57(6):872-877.
[13]Ervin RB.Prevalence of metabolic syndrome among adults 20 years of age and over,by sex,age,race and ethnicity,and body mass index:United States,2003-2006[J].National Health Statistics Reports,2009,5(13):1-7.
[14]胡宾,周玉杰.代谢综合征发病机制的研究进展[J].中华老年心脑血管病杂志,2012,14(3):336-337.
[15]高霞,张菊英,王敏,等.四川省城市居民慢性病患病率及影响因素分析[J].现代预防医学,2007,34(20):3821-3822,3827.
[16]Stefani KM,Kim HC,Kim J,et al.The influence of sex and age on the relationship between sleep duration and metabolic syndrome in Korean adults[J].Diabetes Research and Clinical Practice,2013,102(3):250-259.
[17]孙训明,胡淑娟,姚舜,等.午睡与高血压的相关性[J].中华高血压杂志,2016(4):329-333.
[18]李志强,吴东妮,肖艳杰,等.睡眠与2型糖尿病关系的病例对照研究[J].现代预防医学,2012,39(19):5046-5047,5051.
[19]Shan ZL,Ma HF,Xie ML,et al.Sleep duration and risk of type 2 diabetes:a meta-analysis of prospective studies[J].Diabetes Care,2015,38(3):529-537.
[20]Fang J,Wheaton AG,Keenan NL,et al.Association of sleep duration and hypertension among US adults varies by age and sex[J].American Journal of Hypertension,2012,25(3):335-341.
[21]Cao Z,Shen L,Wu J,et al.The effects of midday nap duration on the risk of hypertension in a middle-aged and older Chinese population:a preliminary evidence from the Tongji-Dongfeng Cohort Study,China[J].Journal of Hypertension,2014,32(10):1993-1998.