气相色谱法测定防晒化妆品中14种防晒剂的含量
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摘要
采用甲醇超声萃取防晒化妆品中防晒剂,经DB-5MS毛细管色谱柱分离,氢火焰离子化检测器测定,建立了气相色谱法同时测定防晒化妆品中14种防晒剂的检测方法。结果表明:14种防晒剂在0.5~100.0mg/kg范围内线性关系良好,相关系数(r~2)≥0.9993;检出限为0.05~0.15mg/kg,定量限为0.17~0.50mg/kg;加标回收率为91.7%~100.1%,相对标准偏差为1.1%~3.1%。该法操作简便、加标回收率高、精密度好、检出限低,可为防晒化妆品中防晒剂的种类和含量测定提供参考。
A method for simultaneous determination of 14 sunscreen agents in sunscreen cosmetics was established by gas chromatography, with ultrasonic extraction of sunscreen agents in sunscreen cosmetics carried out by DB-5 MS capillary column separation and hydrogen flame ionization detector. The results show that the linearity of 14 sunscreen agents is good in the range of 0.5-100.0 mg/kg, and the correlation coefficients are more than 0.999 3. The detection limit is 0.05-0.15 mg/kg, the limit of quantification is 0.17-0.50 mg/kg; the relative standard deviation is 1.1%-3.1%, and the recovery rate of the spiked standards are 91.7%-100.1%. The method has the advantages of simple operation, high recovery rate, good precision and low detection limit, and can provide a detection method for determining the type and content of the sunscreen agent in the sunscreen cosmetic.
A method for simultaneous determination of 14 sunscreen agents in sunscreen cosmetics was established by gas chromatography, with ultrasonic extraction of sunscreen agents in sunscreen cosmetics carried out by DB-5 MS capillary column separation and hydrogen flame ionization detector. The results show that the linearity of 14 sunscreen agents is good in the range of 0.5-100.0 mg/kg, and the correlation coefficients are more than 0.999 3. The detection limit is 0.05-0.15 mg/kg, the limit of quantification is 0.17-0.50 mg/kg; the relative standard deviation is 1.1%-3.1%, and the recovery rate of the spiked standards are 91.7%-100.1%. The method has the advantages of simple operation, high recovery rate, good precision and low detection limit, and can provide a detection method for determining the type and content of the sunscreen agent in the sunscreen cosmetic.
引文
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[15]Xu Xiumin,Gao Yanhong,Long Chaoyang,et al.Determination of15 UV filters in cosmetics by HPLC[J].Chinese Journal of Health Laboratory Technology,2011,21(7):1601-1606.
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[17]Li Ying,Wang Chengyun,Liu Li,et al.Determination of sunscreen agents in cosmetics by gas chromatography/mass spectrometry[J].Chinese Journal of Analysis Laboratory,2003,22(3):77-80.
[18]Ding Yiran,Huang Yun,Zhao Tingting,et al.Determination of five representative ultraviolet filters in water by gas chromatographymass spectrometry[J].Chinese Journal of Chromatography,2014,32(6):629-634.
[2]Gao Lixue,Zhang Lixia.Contents of sunscreen agents in cosmetic products[J].Chinese Journal of Public Health,2011,27(6):785-786.
[3]Gao Lixue,Zhang Weiqiang,Yu Xiaoyi.Analysis of frequency on the use of sunscreen agents in cosmetic products[J].Modern Preventive Medicine,2011,38(7):1324-1332.
[4]Yang Yanwei,Liu Siran,Luo Song,et al.Investigation on sunscreens in cosmetics[J].Journal of Environmental Hygiene,2015,5(2):139-142.
[5]Sukyoung Heo,Hee SookHwang,Yohan Jeong,et al.Skin protection efficacy from UV irradiation and skin penetration property of polysaccharide-benzophenone conjugates as a sunscreen agent[J].Carbohydrate Polymers,2018,195(9):534-541.
[6]Latha M S,Martis J,Shobha V,et al.Sunscreening agents:a review[J].The Journal of Clinical and Aesthetic Dermatology,2013,6(1):16-26.
[7]Baker L A,Horbury M D,Stavros V G.Ultrafast photoprotective properties of the sunscreening agent octocrylene[J].Optics Express,2016,24(10):10700-10709.
[8]Zheng Jie.Properties and quality evaluation of sunscreen[J].Detergent&Cosmetics,2010,33(8):18-21.
[9]Gao Li,Yuan Tao,Wang Wenhua.Ecological risk assessment of organic UV filters in aquatic environment[J].Journal of Environment and Health,2015,32(4):332-336.
[10]Cao Jinfang,Zhou Jie.Determination of light-stability of sunscreen agents and sunprotect agent blends[J].China Surfactant Detergent&Cosmetics,2004,34(4):259-261.
[11]Figueiredo S A,Moraes D C,Vilela F M P,et al.A novel research model for evaluating sunscreen protection in the UV-A1[J].Journal of Photochemistry and Photobiology B:Biology,2018,178(10):61-68.
[12]Xu Huijin,Lin Feng,Wu Yingxuan.HPLC determination of9 ultraviolet absorbents in cosmetics[J].Physical Testing and Chemical Analysis part B:Chemical Analysis,2015,51(5):621-624.
[13]Xu Li,Pang Daobiao,Fu Lingmei,et al.UPC2 determination of7 sunscreeners in cosmetics[J].Physical Testing and Chemical Analysis part B:Chemical Analysis,2015,51(12):1666-1669.
[14]Yu Chenghua,Chao Qiangguo,Cao Chengming,et al.HPLCdetermination of tanning preventives in cosmetics[J].Physical Testing and Chemical Analysis Part B:Chemical Analysis,2010,46(11):1273-1278.
[15]Xu Xiumin,Gao Yanhong,Long Chaoyang,et al.Determination of15 UV filters in cosmetics by HPLC[J].Chinese Journal of Health Laboratory Technology,2011,21(7):1601-1606.
[16]Zhang Kedong,Li Huiyong,Tan Jianhua,et al.Determination of 9 kinds of PABA and ester sunscreens in cosmetics by high performance liquid chromatography[J].Chinese Journal of Analysis Laboratory,2014,33(9):1108-1113.
[17]Li Ying,Wang Chengyun,Liu Li,et al.Determination of sunscreen agents in cosmetics by gas chromatography/mass spectrometry[J].Chinese Journal of Analysis Laboratory,2003,22(3):77-80.
[18]Ding Yiran,Huang Yun,Zhao Tingting,et al.Determination of five representative ultraviolet filters in water by gas chromatographymass spectrometry[J].Chinese Journal of Chromatography,2014,32(6):629-634.