有氧运动联合抗阻训练对2型糖尿病患者氧化应激及糖脂代谢的影响
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摘要
目的:分析有氧运动联合抗阻训练对2型糖尿病患者氧化应激及糖脂代谢的影响。方法:将符合标准的105例2型糖尿病患者随机分组,对照组52例进行有氧运动,观察组53例加用抗阻训练,2组均持续训练3个月,观察2组患者训练前后氧化应激及糖脂代谢相关指标的变化。结果:观察组FPG、HbAlc、TC、LDL-C、MDA及8-OHdG均低于对照组,SOD高于对照组,差异具有统计学意义(P<0.05)。结论:有氧联合抗阻训练能有效控制2型糖尿病患者血糖、血脂水平,改善患者糖脂代谢及氧化应激,其效果优于单纯有氧运动。
Objectives: To analyze the effects of aerobic exercise combined with resistance training on oxidative stress and glycolipid metabolism in patients with type 2 diabetes. Methods: A total of 105 patients with type 2 diabetes who met the criteria were randomized. A total of 52 patients in the control group underwent aerobic exercise. Antiresistance training was added to 53 patients in the observation group. Both groups continued to train for 3 months. The changes of oxidative stress and glucose and lipid metabolism related indexes before and after training were observed.Results: The FPG, HbAlc, TC, LDL-C, MDA and 8-OHdG in the observation group were lower than those in the control group, and the SOD was higher than that in the control group(P<0.05). Conclusion: Aerobic combined resistance training can effectively control blood sugar and blood lipid levels in patients with type 2 diabetes, improve glucose and lipid metabolism and oxidative stress, and its effect is better than simple aerobic exercise.
Objectives: To analyze the effects of aerobic exercise combined with resistance training on oxidative stress and glycolipid metabolism in patients with type 2 diabetes. Methods: A total of 105 patients with type 2 diabetes who met the criteria were randomized. A total of 52 patients in the control group underwent aerobic exercise. Antiresistance training was added to 53 patients in the observation group. Both groups continued to train for 3 months. The changes of oxidative stress and glucose and lipid metabolism related indexes before and after training were observed.Results: The FPG, HbAlc, TC, LDL-C, MDA and 8-OHdG in the observation group were lower than those in the control group, and the SOD was higher than that in the control group(P<0.05). Conclusion: Aerobic combined resistance training can effectively control blood sugar and blood lipid levels in patients with type 2 diabetes, improve glucose and lipid metabolism and oxidative stress, and its effect is better than simple aerobic exercise.
引文
[1]汪会琴,胡如英,武海滨,等.2型糖尿病报告发病率研究进展[J].浙江预防医学,2016,28(1):37-39,57.
[2]陈颖,夏明锋,李小英.体脂分布与糖尿病风险[J].中华糖尿病杂志,2017,9(4):218-220.
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[5]金仙,陈晓平.2型糖尿病合并肥胖人群的胰岛素应用[J].中华全科医师杂志,2019,18(1):17-20.
[6]陆丽荣,戴霞,陈青云,等.联合抗阻—有氧运动对糖尿病前期人群代谢指标的影响[J].广西医科大学学报,2016,33(1):57-59.
[7]宋爱华,韩玉芹,夏引芳,等.中等强度有氧运动对社区2型糖尿病病人糖代谢水平及相关指标的影响[J].护理研究,2012,26(12):3354-3355.
[8]罗曦娟,王正珍,朱玲,等.有氧和抗阻运动对糖尿病前期人群血糖干预效果的比较研究[J].中国运动医学杂志,2015,34(9):831-837.
[9]余萍,季鹏,胡树罡,等.个体化有氧联合抗阻运动对冠心病并发2型糖尿病患者血糖、血脂以及运动能力的影响[J].岭南心血管病杂志,2017,23(5):525-529.
[10]吴伟,张玲莉,邹军.中药多糖及运动抗氧化作用对糖尿病防治的研究进展[J].中国中药杂志,2016,41(14):2591-2599.
[11]朱剑兰.利拉鲁肽治疗初诊超重或肥胖2型糖尿病的疗效与体质指数、血脂及炎性因子变化[J].菏泽医学专科学校学报,2017,29(4):36-38,95.
[12]许聿新,井庆平,赵翠红.有氧联合抗阻运动对老年2型糖尿病患者氧化应激及糖脂代谢的影响[J].中国老年学杂志,2019,39(3):591-593.
[2]陈颖,夏明锋,李小英.体脂分布与糖尿病风险[J].中华糖尿病杂志,2017,9(4):218-220.
[3]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2007年版)[J].中华医学杂志,2008,88(18):1227-1245.
[4]南敏,李文慧.胰升糖素不适当分泌增多在2型糖尿病发病中的作用[J].中国医学科学院学报,2018,40(3):421-426.
[5]金仙,陈晓平.2型糖尿病合并肥胖人群的胰岛素应用[J].中华全科医师杂志,2019,18(1):17-20.
[6]陆丽荣,戴霞,陈青云,等.联合抗阻—有氧运动对糖尿病前期人群代谢指标的影响[J].广西医科大学学报,2016,33(1):57-59.
[7]宋爱华,韩玉芹,夏引芳,等.中等强度有氧运动对社区2型糖尿病病人糖代谢水平及相关指标的影响[J].护理研究,2012,26(12):3354-3355.
[8]罗曦娟,王正珍,朱玲,等.有氧和抗阻运动对糖尿病前期人群血糖干预效果的比较研究[J].中国运动医学杂志,2015,34(9):831-837.
[9]余萍,季鹏,胡树罡,等.个体化有氧联合抗阻运动对冠心病并发2型糖尿病患者血糖、血脂以及运动能力的影响[J].岭南心血管病杂志,2017,23(5):525-529.
[10]吴伟,张玲莉,邹军.中药多糖及运动抗氧化作用对糖尿病防治的研究进展[J].中国中药杂志,2016,41(14):2591-2599.
[11]朱剑兰.利拉鲁肽治疗初诊超重或肥胖2型糖尿病的疗效与体质指数、血脂及炎性因子变化[J].菏泽医学专科学校学报,2017,29(4):36-38,95.
[12]许聿新,井庆平,赵翠红.有氧联合抗阻运动对老年2型糖尿病患者氧化应激及糖脂代谢的影响[J].中国老年学杂志,2019,39(3):591-593.