低分子肝素加用生长抑素治疗高脂性重症胰腺炎效果及其对炎症因子水平影响
摘要
<正>急性胰腺炎(acute pancreatitis)是指多种病因所致胰酶在胰腺内被激活后引起胰腺组织自身消化、水肿、出血甚至坏死的炎症反应~([1])。因高脂血症可使得血液黏稠而易出现胰腺血管栓塞,栓塞可导致胰腺微循环障碍进一步加重胰腺组织损伤坏死,形成恶性循环~([2])。本文旨在研究低分子肝素与生长抑素联用时对合并高脂血症性胰腺炎的临床疗效及其对相应炎症因子水平的影响,现报告如下。1资料与方法1.1病例资料:收集2014年1月至2017年2月浙江天台人
引文
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[2] van Dijk SM,Hallensleben NDL,van Santvoort HC,et al. Acute pancreatitis:recent advances through randomised trials[J]. Gut,2017,66(11):2024-2032.
[3]中华医学会消化病学分会胰腺疾病学组.中国急性胰腺炎诊治指南(2013年,上海)[J].中华消化杂志,2013,4(33):217-222.
[4] He WH,Yu M,Zhu Y,et al. Emergent triglyceride-lowering therapy with early high-volume hemofiltration against low-molecular-weight heparin combined with insulin in hypertriglyceridemic pancreatitis:a prospective randomized controlled trial[J]. J Clin Gastroenterol,2016,50(9):772-778.
[5] Wang G,Xiao G,Xu L,et al. Effect of somatostatin on prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis and hyperamylasemia:a systematic review and meta-analysis[J]. Pancreatology,2018,18(4):370-378.