ISN/RPS狼疮性肾炎病变定义及分型修订共识
|
摘要
2016年,在荷兰莱顿大学召开了由18名成员参加的国际肾脏病理学工作组会议,会议提出对狼疮性肾炎(LN)病变定义和分型进行修订第一阶段,对LN的部分病变包括系膜细胞增多,细胞、纤维细胞和纤维性新月体等病变定义做了修订。把"毛细血管内增殖"(endocapillary proliferation)修订为"毛细血管内细胞增多"(endocapillary hypercellularity)。取消LN-Ⅳ球性(G)和节段(S)亚型的分类。LN-Ⅲ和Ⅳ中活动性(A)和慢性化(C)名称修订为NIH活动性和慢性化指数评分。活动性指数评分中包含纤维素样坏死。针对目前证据不足及有争议的问题,将在第二阶段利用临床病理研究来探讨,对新修订定义的病变和分型的可重复性及意义进行观察验证。
引文
1 Weening JJ,D′Agati VD,Schwartz MM,et al.The classification of glomerulonephritis in systemic lupus erythematosus revisited.J Am Soc Nephrol,2004,15(2):241-250.
2 Working Group of the International IgA Nephropathy Network and the Renal Pathology Society,Cattran DC,Coppo R,Cook HT,et al.The Oxford classification of IgA nephropathy: rationale,clinicopathological correlations,and classification.Kidney Int,2009,76(5):534-545.
3 Working Group of the International IgA Nephropathy Network and the Renal Pathology Society,Roberts IS,Cook HT,Troyanov S,et al.The Oxford classification of IgA nephropathy: pathology definitions,correlations,and reproducibility.Kidney Int,2009,76(5):546-556.
4 TrimarchiH,Barratt J,Cattran DC,et al.Oxford Classification of IgA nephropathy 2016: an update from the IgA Nephropathy Classification Working Group.Kidney Int,2017,91(5):1014-1021.
5 Berden AE,Ferrario F,Hagen EC,et al.Histopathologic classification of ANCA-associated glomerulonephritis.J Am Soc Nephrol,2010,21(10):1628-1636.
6 Barisoni L,Troost JP,Nast C,et al.Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images.Mod Pathol,2016,29(7):671-684.
7 JC Jennette CCSCC.NIH/NIDDK Cure Glomerulonephropathy Network (CureGN).Provided by CureGN Core Scoring Committee Chair.
8 Loupy A,Haas M,Solez K,et al.The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology.Am J Transplant,2017;17(1):28-41.
9 Haring CM,Rietveld A,van den Brand JA,et al.Segmental and global subclasses of class IV lupus nephritis have similar renal outcomes.J Am Soc Nephrol,2012,23(1):149-154.
10 Wilhelmus S,Cook HT,No?l LH,et al.Interobserver agreement on histopathological lesions in class III or IV lupus nephritis.Clin J Am Soc Nephrol,2015,10(1):47-53.
11 Wilhelmus S,Alpers CE,Cook HT,et al.The Revisited Classification of GN in SLE at 10 Years: Time to Re-Evaluate Histopathologic Lesions.J Am Soc Nephrol,2015,26(12):2938-2946.
12 Bajema IM,Wilhelmus S,Alpers CE,et al.Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions,and modified National Institutes of Health activity and chronicity indices.Kidney Int,2018,93(4):789-796.
13 Nasr SH,D′Agati VD,Park HR,et al.Necrotizing and crescentic lupus nephritis with antineutrophil cytoplasmic antibody seropositivity.Clin J Am Soc Nephrol.2008,3(3):682-690.
14 Austin HA 3rd,Muenz LR,Joyce KM,et al.Diffuse proliferative lupus nephritis: identification of specific pathologic features affecting renal outcome.Kidney Int,1984,25(4):689-695.
15 Bhathena DB,Sobel BJ,Migdal SD.Noninflammatory renal microangiopathy of systemic lupus erythematosus (′lupus vasculitis′).Am J Nephrol,1981,1(3-4):144-159.
16 Appel GB,Pirani CL,D′Agati V.Renal vascular complications of systemic lupus erythematosus.J Am Soc Nephrol,1994,4(8):1499-1515.
17 Wu LH,Yu F,Tan Y,et al.Inclusion of renal vascular lesions in the 2003 ISN/RPS system for classifying lupus nephritis improves renal outcome predictions.Kidney Int,2013,83(4):715-723.
2 Working Group of the International IgA Nephropathy Network and the Renal Pathology Society,Cattran DC,Coppo R,Cook HT,et al.The Oxford classification of IgA nephropathy: rationale,clinicopathological correlations,and classification.Kidney Int,2009,76(5):534-545.
3 Working Group of the International IgA Nephropathy Network and the Renal Pathology Society,Roberts IS,Cook HT,Troyanov S,et al.The Oxford classification of IgA nephropathy: pathology definitions,correlations,and reproducibility.Kidney Int,2009,76(5):546-556.
4 TrimarchiH,Barratt J,Cattran DC,et al.Oxford Classification of IgA nephropathy 2016: an update from the IgA Nephropathy Classification Working Group.Kidney Int,2017,91(5):1014-1021.
5 Berden AE,Ferrario F,Hagen EC,et al.Histopathologic classification of ANCA-associated glomerulonephritis.J Am Soc Nephrol,2010,21(10):1628-1636.
6 Barisoni L,Troost JP,Nast C,et al.Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images.Mod Pathol,2016,29(7):671-684.
7 JC Jennette CCSCC.NIH/NIDDK Cure Glomerulonephropathy Network (CureGN).Provided by CureGN Core Scoring Committee Chair.
8 Loupy A,Haas M,Solez K,et al.The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology.Am J Transplant,2017;17(1):28-41.
9 Haring CM,Rietveld A,van den Brand JA,et al.Segmental and global subclasses of class IV lupus nephritis have similar renal outcomes.J Am Soc Nephrol,2012,23(1):149-154.
10 Wilhelmus S,Cook HT,No?l LH,et al.Interobserver agreement on histopathological lesions in class III or IV lupus nephritis.Clin J Am Soc Nephrol,2015,10(1):47-53.
11 Wilhelmus S,Alpers CE,Cook HT,et al.The Revisited Classification of GN in SLE at 10 Years: Time to Re-Evaluate Histopathologic Lesions.J Am Soc Nephrol,2015,26(12):2938-2946.
12 Bajema IM,Wilhelmus S,Alpers CE,et al.Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions,and modified National Institutes of Health activity and chronicity indices.Kidney Int,2018,93(4):789-796.
13 Nasr SH,D′Agati VD,Park HR,et al.Necrotizing and crescentic lupus nephritis with antineutrophil cytoplasmic antibody seropositivity.Clin J Am Soc Nephrol.2008,3(3):682-690.
14 Austin HA 3rd,Muenz LR,Joyce KM,et al.Diffuse proliferative lupus nephritis: identification of specific pathologic features affecting renal outcome.Kidney Int,1984,25(4):689-695.
15 Bhathena DB,Sobel BJ,Migdal SD.Noninflammatory renal microangiopathy of systemic lupus erythematosus (′lupus vasculitis′).Am J Nephrol,1981,1(3-4):144-159.
16 Appel GB,Pirani CL,D′Agati V.Renal vascular complications of systemic lupus erythematosus.J Am Soc Nephrol,1994,4(8):1499-1515.
17 Wu LH,Yu F,Tan Y,et al.Inclusion of renal vascular lesions in the 2003 ISN/RPS system for classifying lupus nephritis improves renal outcome predictions.Kidney Int,2013,83(4):715-723.