百日咳综合征的概念及诊疗进展
摘要
<正>儿童咳嗽是临床最常见的症状,病因多种多样,以感染最为多见。近年来,许多发达和发展中国家均出现了百日咳增多的现象,不仅见于婴儿、儿童,也可见于成人;人们称之为"百日咳再现",原因多种多样~([1,2])。这种情况增加了人们对百日咳的重视。不过,目前相当多的医院并没有检测百日咳病原的实验室条件,只能根据临床表现作出疑似诊断,成为临床医师经常面对的难
引文
[1]黄海涛,高志刚,刘勇,等.天津市2005-2014年成年人百日咳流行特征及相关因素分析[J].中华流行病学杂志,2016,37(5):678-681.
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[3]中华医学会儿科学分会感染学组,《中华儿科杂志》编辑委员会.中国儿童百日咳诊断及治疗建议[J].中华儿科杂志,2017,55(8):568-572.
[4]王真行,邹力.WHO关于百日咳疫苗的意见书[J].国际生物制品学杂志,2016,39(2):97-103.
[5]Leber AL.Pertussis:relevant species and diagnostic update[J].Clin Lab Med,2014,34(2):237-255.
[6]Mooi FR,Bruisten S,Linde I,et al.Characterization of Bordetella holmesii isolates from patients with pertussis-like illness in The Netherlands[J].FEMS Immunol Med Microbiol,2012,64(2):289-291.
[7]Mahmoudi S,Banar M,Pourakbari B,et al.Identification of Etiologic Agents of the Pertussis-like Syndrome in Children by Real-time PCRMethod[J].Prague Med Rep,2018,119(1):61-69.
[8]Al Maani A,Al Qayoudhi A,Nazir HF,et al.Pertussis and Pertussis like Illness:Pediatric Experience in Oman[J].Oman Med J,2017,32(5):396-402.
[9]张喜凤.小儿百日咳综合征的临床特点及治疗分析[J].中国继续医学教育,2018,10(9):91-93.
[10]王丽燕,王文棣,范文文,等.青岛地区2012~2014年百日咳综合征发病趋势与临床治疗分析[J].中国临床新医学,2016,9(7):594-598.
[11]Sarbay H,Polat A,Mete E,et al.Pertussis-like syndrome associated with adenovirus presenting with hyperleukocytosis:Case report[J].North Clin Istanb,2016,3(2):140-142.
[12]Fong W,Timms V,Holmes N,et al.Detection and incidence of Bordetella holmesii in respiratory specimens from patients with pertussis-like symptoms in New South Wales,Australia[J].Pathology,2018,50(3):322-326.
[13]Ferrer A,CalicóI,Manresa JM,et al.Microorganisms isolated in cases of pertussis-like syndrome[J].Enferm Infecc Microbiol Clin,2000,18(9):433-438.
[14]黄辉,邓莉,肖飞,等.儿童百日咳发病特点及诊断中联合呼吸道病毒检测的临床意义分析[J].中华儿科杂志,2017,55(8):580-585.
[15]王琨,王宇清,郝创利,等.儿童百日咳与类百日咳综合征的临床特点分析[J].国际儿科学杂志,2018,45(6):470-473.
[16]程燕,陈慧.儿童百日咳样综合征病原临床分析[J].吉林中医药,2014,34(5):478-480.
[17]王江涛,王晓玲,刘榕.小婴儿类百日咳综合征肺炎支原体感染情况及疗效分析[J].中国中西医结合儿科学,2017,9(1):40-43.
[18]吕芳芳,施林微,陈小芳,等.90例2岁以下百日咳疑似患儿病原学及临床特征分析[J].中华传染病杂志,2017,35(10):589-594.
[19]Nguyen VTN,Simon L.Pertussis:The Whooping Cough[J].Prim Care,2018,45(3):423-431.
[20]赵建刚,蔡玉香.新生儿百日咳68例临床分析[J].中华新生儿科杂志(中英文),2017,32(3):201-204.
[21]李丽君,叶金艳,姚开虎.百日咳的实验室诊断方法研究进展[J].中华传染病杂志,2017,35(12):765-768.
[22]邓继岿,王红梅,田树风.儿童百日咳的临床特点及实验室诊断[J].中华实用儿科临床杂志,2017,32(22):1692-1695.
[23]唐铭钰,李锦,干驰,等.婴儿疑似百日咳的临床特征及病原比较分析[J].中国小儿急救医学,2018,25(5):367-371.
[24]Morton T,Birtwistle C,Fumerton R,et al.Large pertussis outbreak in rural Canada:Lessons learned from Haida Gwaii[J].Can Fam Physician,2018,64(7):e317-e324.
[25]杨永弘,杨颖.百日咳杆菌耐药[J].中华实用儿科临床杂志,2016,31(4):263-265.
[26]张娟胜,李芳,栾阳,等.百日咳鲍特菌23S rRNA位点变异AS-PCR检测方法建立[J].中国公共卫生,2018,34(6):923-926.
[27]杜天华,彭韶.甲泼尼龙及维生素K1治疗百日咳综合征的疗效观察[J].中国实用医刊,2016,43(3):51-52.
[28]李玉华,薛秀丽,左继华,等.早期应用丙种球蛋白治疗婴儿百日咳样综合征临床疗效观察[J].河北医学,2016,22(11):1886-1887.
[29]刘玉慧,陈文霞,相恒杰,等.中西医结合治疗婴幼儿类百日咳综合征临床观察[J].中医临床研究,2016,8(19):95-96.
[30]刘东旺.中西医结合疗法用于百日咳综合征的临床分析[J].内蒙古中医药,2017,36(17):48-49.
[31]Del Valle-Mendoza J,Silva-Caso W,Aguilar-Luis MA,et al.Bordetella pertussis in children hospitalized with a respiratory infection:clinical characteristics and pathogen detection in household contacts[J].BMC Res Notes,2018,11(1):318.
[32]Takajo D,Nonoyama S.Severe pertussis in a young infant due to household transmission:the needs of pertussis vaccination boosters in Japan[J].Clin Case Rep,2018,6(5):810-812.
[33]Esposito S,Principi N.Prevention of pertussis:An unresolved problem[J].Hum Vaccin Immunother,2018,14(10):2452-2459.
[34]Meng QH,Liu Y,Yu JQ,et al.Seroprevalence of Maternal and Cord Antibodies Specific for Diphtheria,Tetanus,Pertussis,Measles,Mumps and Rubella in Shunyi,Beijing[J].Sci Rep,2018,8(1):13021.
[35]Hirai K,Homma T,Yamaguchi F,et al.Acute exacerbation of idiopathic pulmonary fibrosis induced by pertussis:the first case report[J].BMC Pulm Med,2019,19(1):15.
[2]刘莹,姚开虎.百日咳再现的研究进展[J].中华儿科杂志,2018,56(4):313-316.
[3]中华医学会儿科学分会感染学组,《中华儿科杂志》编辑委员会.中国儿童百日咳诊断及治疗建议[J].中华儿科杂志,2017,55(8):568-572.
[4]王真行,邹力.WHO关于百日咳疫苗的意见书[J].国际生物制品学杂志,2016,39(2):97-103.
[5]Leber AL.Pertussis:relevant species and diagnostic update[J].Clin Lab Med,2014,34(2):237-255.
[6]Mooi FR,Bruisten S,Linde I,et al.Characterization of Bordetella holmesii isolates from patients with pertussis-like illness in The Netherlands[J].FEMS Immunol Med Microbiol,2012,64(2):289-291.
[7]Mahmoudi S,Banar M,Pourakbari B,et al.Identification of Etiologic Agents of the Pertussis-like Syndrome in Children by Real-time PCRMethod[J].Prague Med Rep,2018,119(1):61-69.
[8]Al Maani A,Al Qayoudhi A,Nazir HF,et al.Pertussis and Pertussis like Illness:Pediatric Experience in Oman[J].Oman Med J,2017,32(5):396-402.
[9]张喜凤.小儿百日咳综合征的临床特点及治疗分析[J].中国继续医学教育,2018,10(9):91-93.
[10]王丽燕,王文棣,范文文,等.青岛地区2012~2014年百日咳综合征发病趋势与临床治疗分析[J].中国临床新医学,2016,9(7):594-598.
[11]Sarbay H,Polat A,Mete E,et al.Pertussis-like syndrome associated with adenovirus presenting with hyperleukocytosis:Case report[J].North Clin Istanb,2016,3(2):140-142.
[12]Fong W,Timms V,Holmes N,et al.Detection and incidence of Bordetella holmesii in respiratory specimens from patients with pertussis-like symptoms in New South Wales,Australia[J].Pathology,2018,50(3):322-326.
[13]Ferrer A,CalicóI,Manresa JM,et al.Microorganisms isolated in cases of pertussis-like syndrome[J].Enferm Infecc Microbiol Clin,2000,18(9):433-438.
[14]黄辉,邓莉,肖飞,等.儿童百日咳发病特点及诊断中联合呼吸道病毒检测的临床意义分析[J].中华儿科杂志,2017,55(8):580-585.
[15]王琨,王宇清,郝创利,等.儿童百日咳与类百日咳综合征的临床特点分析[J].国际儿科学杂志,2018,45(6):470-473.
[16]程燕,陈慧.儿童百日咳样综合征病原临床分析[J].吉林中医药,2014,34(5):478-480.
[17]王江涛,王晓玲,刘榕.小婴儿类百日咳综合征肺炎支原体感染情况及疗效分析[J].中国中西医结合儿科学,2017,9(1):40-43.
[18]吕芳芳,施林微,陈小芳,等.90例2岁以下百日咳疑似患儿病原学及临床特征分析[J].中华传染病杂志,2017,35(10):589-594.
[19]Nguyen VTN,Simon L.Pertussis:The Whooping Cough[J].Prim Care,2018,45(3):423-431.
[20]赵建刚,蔡玉香.新生儿百日咳68例临床分析[J].中华新生儿科杂志(中英文),2017,32(3):201-204.
[21]李丽君,叶金艳,姚开虎.百日咳的实验室诊断方法研究进展[J].中华传染病杂志,2017,35(12):765-768.
[22]邓继岿,王红梅,田树风.儿童百日咳的临床特点及实验室诊断[J].中华实用儿科临床杂志,2017,32(22):1692-1695.
[23]唐铭钰,李锦,干驰,等.婴儿疑似百日咳的临床特征及病原比较分析[J].中国小儿急救医学,2018,25(5):367-371.
[24]Morton T,Birtwistle C,Fumerton R,et al.Large pertussis outbreak in rural Canada:Lessons learned from Haida Gwaii[J].Can Fam Physician,2018,64(7):e317-e324.
[25]杨永弘,杨颖.百日咳杆菌耐药[J].中华实用儿科临床杂志,2016,31(4):263-265.
[26]张娟胜,李芳,栾阳,等.百日咳鲍特菌23S rRNA位点变异AS-PCR检测方法建立[J].中国公共卫生,2018,34(6):923-926.
[27]杜天华,彭韶.甲泼尼龙及维生素K1治疗百日咳综合征的疗效观察[J].中国实用医刊,2016,43(3):51-52.
[28]李玉华,薛秀丽,左继华,等.早期应用丙种球蛋白治疗婴儿百日咳样综合征临床疗效观察[J].河北医学,2016,22(11):1886-1887.
[29]刘玉慧,陈文霞,相恒杰,等.中西医结合治疗婴幼儿类百日咳综合征临床观察[J].中医临床研究,2016,8(19):95-96.
[30]刘东旺.中西医结合疗法用于百日咳综合征的临床分析[J].内蒙古中医药,2017,36(17):48-49.
[31]Del Valle-Mendoza J,Silva-Caso W,Aguilar-Luis MA,et al.Bordetella pertussis in children hospitalized with a respiratory infection:clinical characteristics and pathogen detection in household contacts[J].BMC Res Notes,2018,11(1):318.
[32]Takajo D,Nonoyama S.Severe pertussis in a young infant due to household transmission:the needs of pertussis vaccination boosters in Japan[J].Clin Case Rep,2018,6(5):810-812.
[33]Esposito S,Principi N.Prevention of pertussis:An unresolved problem[J].Hum Vaccin Immunother,2018,14(10):2452-2459.
[34]Meng QH,Liu Y,Yu JQ,et al.Seroprevalence of Maternal and Cord Antibodies Specific for Diphtheria,Tetanus,Pertussis,Measles,Mumps and Rubella in Shunyi,Beijing[J].Sci Rep,2018,8(1):13021.
[35]Hirai K,Homma T,Yamaguchi F,et al.Acute exacerbation of idiopathic pulmonary fibrosis induced by pertussis:the first case report[J].BMC Pulm Med,2019,19(1):15.