梅花针叩刺手足阳明经联合维A酸乳膏治疗寻常性痤疮(湿热蕴结)随机平行对照研究
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摘要
[目的]观察梅花针叩刺手足阳明经联合维A酸乳膏治疗寻常性痤疮(湿热蕴结)疗效。[方法]使用随机平行对照方法,将70例门诊患者按就诊顺序号抽签随机分为两组。对照组35例维A酸乳膏,痤疮局部外涂,2次/d。治疗组35例梅花针叩刺,充分暴露针刺处皮肤,常规消毒,医者手握梅花针后端,食指伸直按压针柄,针尾在腕部横纹之上,针头与皮肤垂直,选取面部、背部痤疮密集处及手足阳明经叩刺,重点穴位叩刺约1min,60～80次/min,以皮肤表面轻潮红为度,3次/周;维A酸乳膏治疗同对照组。连续治疗4周为1疗程。观测临床表现、症状积分、不良反应。治疗1疗程(4周),判定疗效。[结果]治疗组痊愈6例,显效12例,有效15例,无效2例,总有效率94.29%;对照组痊愈3例,显效9例,有效15例,无效8例,总有效率77.14%;治疗组疗效优于对照组(P<0.05)。(粉刺、丘疹)、(脓疱、结节)、皮损两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]梅花针叩刺手足阳明经联合维A酸乳膏治疗寻常性痤疮(湿热蕴结),疗效满意,无严重不良反应,值得推广。
[Objective] To observe the efficacy of percussopunctator prick at hand-foot-yangming meridian combined with vitamin A acid cream on acne vulgaris(damp-heat accumulation). [Methods] Using randomized parallel controlled method, 70 outpatients were randomly divided into two groups according to the order of treatment. 35 cases in control group were given vitamin A acid cream for topical external application of acne(twice/d), and 35 cases in treatment group were given percussopunctator prick(specific process: the skin of acupuncture was fully exposed, routine disinfection was performed, the end of percussopunctator was held by doctor, the needle handle was pressed by straightened index finger, the needle tail was above the wrist transverse line, the needle head was perpendicular to the skin, and the face and back acne intensive areas and hand-foot yangming meridian were selected for percussopunctator prick, and key point prick about1 min, 60～80 times/min, the skin surface of light red color, 3 times/w). And vitamin A acid cream was given to control group, and they were continuously treated for 4 w as 1 course of treatment. The clinical manifestations,symptoms scores and adverse reactions were observed and measured. At 1 course of treatment(4 w), the efficacy was determined. [Results] In treatment group, there were 6 cured cases, 12 markedly effective cases,15 effective cases and 2 ineffective cases, and the total effective rate was 94.29%. In control group, there were 3 cured cases, 9 markedly effective cases, 15 effective cases and 8 ineffective cases, and the total effective rate was 77.14%. The efficacy in treatment group was better than that in control group(P<0.05). The skin lesions(Acne, pimples),(pustules, nodules) were improved in the two groups(P<0.01), and the improvement in treatment group was better than that in control group(P<0.01). [Conclusion] Percussopunctator prick at hand-foot-yangming meridian combined with vitamin A acid cream has satisfactory efficacy and no serious adverse reactions in the treatment of acne vulgaris(damp-heat accumulation), thus it is worth promoting.
[Objective] To observe the efficacy of percussopunctator prick at hand-foot-yangming meridian combined with vitamin A acid cream on acne vulgaris(damp-heat accumulation). [Methods] Using randomized parallel controlled method, 70 outpatients were randomly divided into two groups according to the order of treatment. 35 cases in control group were given vitamin A acid cream for topical external application of acne(twice/d), and 35 cases in treatment group were given percussopunctator prick(specific process: the skin of acupuncture was fully exposed, routine disinfection was performed, the end of percussopunctator was held by doctor, the needle handle was pressed by straightened index finger, the needle tail was above the wrist transverse line, the needle head was perpendicular to the skin, and the face and back acne intensive areas and hand-foot yangming meridian were selected for percussopunctator prick, and key point prick about1 min, 60～80 times/min, the skin surface of light red color, 3 times/w). And vitamin A acid cream was given to control group, and they were continuously treated for 4 w as 1 course of treatment. The clinical manifestations,symptoms scores and adverse reactions were observed and measured. At 1 course of treatment(4 w), the efficacy was determined. [Results] In treatment group, there were 6 cured cases, 12 markedly effective cases,15 effective cases and 2 ineffective cases, and the total effective rate was 94.29%. In control group, there were 3 cured cases, 9 markedly effective cases, 15 effective cases and 8 ineffective cases, and the total effective rate was 77.14%. The efficacy in treatment group was better than that in control group(P<0.05). The skin lesions(Acne, pimples),(pustules, nodules) were improved in the two groups(P<0.01), and the improvement in treatment group was better than that in control group(P<0.01). [Conclusion] Percussopunctator prick at hand-foot-yangming meridian combined with vitamin A acid cream has satisfactory efficacy and no serious adverse reactions in the treatment of acne vulgaris(damp-heat accumulation), thus it is worth promoting.
引文
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[9]关斌,向芳,梁俊琴,等.寻常性痤疮患者心理健康分析[J].中国美容医学,2014,23(11):934-935.
[10]游弋,郝飞.维A酸类药物的分类及药理作用[J].皮肤病与性病,2018,40(2):25-26.
[11]刘叶兰.中医对寻常痤疮病因病机的认识[J].河南中医,200626(4):6-7.
[12]陈静,张幼明,兰颖.梅花针的临床应用述论[J].湖北中医杂志,2011,33(5):50-51.
[13]黄帝内经素问[M].北京:人民卫生出版社,2012:197.
[14]巩小丽.梅花针叩刺在皮肤病的临床应用[J].甘肃医药,2014,33(6):450-451.
[15]滕秀香,濮凌云.柴松岩“二阳致病”学术思想及临床经验解析[J].中医药信息,2015,32(1):65-66.
[16]巩小丽.梅花针叩刺在皮肤病的临床应用[J].甘肃医药,2014,33(6):450-451.
[17]魏波,江泓成.梅花针面部叩刺治疗重度痤疮100例[J].暨南大学学报(自然科学与医学版),2004,25(2):244-245.
[18]黄敏婷,郑光珊,韦斌,等.梅花针放血对Ⅱ度寻常性痤疮疗效观察[J].广西中医药,2018,41(3):38-39.
[19]张琳,吴凡,薛岚显,等.电梅花针叩刺疗法治疗寻常型痤疮的对照研究[J].时珍国医国药,2014,25(11):2817-2818.
[2]阎德文.浅谈痤疮的发病,辨证与分型诊断[J].深圳中西医结合杂志,2000,10(1):70-71.
[3]中华人民共和国卫生部.涉及人的生物医学研究伦理审查办法(试行)[S].(2007-03-26)[2017-03-01].http://www.moh.gov.cn/qjjys/s3581/200804/b9f1bfee4ab344ec892e68097296e2a8.shtml.
[4]赵辨.临床皮肤病学[M].2版.南京:江苏科学技术出版社,1992:833.
[5]中国医师协会皮肤科医师分会,中西医皮肤科亚专业委员会.中成药治疗寻常痤疮专家共识(2016)[J].中华皮肤科杂志,2016,49(8):533-536.
[6]国家中医药管理局.中药新药临床研究指导原则(试行)[M].北京中国医药科技出版社,2002:291-295.
[7]徐恩佩,汪小敏,张建平,等.1008例寻常性痤疮临床分析[J].中国麻风皮肤病杂志,2004,20(4):396.
[8]毛越苹,尹若非,黄茂芳,等.502例寻常型痤疮临床及相关因素分析[J].皮肤性病诊疗学杂志,2005,12(2):96-99.
[9]关斌,向芳,梁俊琴,等.寻常性痤疮患者心理健康分析[J].中国美容医学,2014,23(11):934-935.
[10]游弋,郝飞.维A酸类药物的分类及药理作用[J].皮肤病与性病,2018,40(2):25-26.
[11]刘叶兰.中医对寻常痤疮病因病机的认识[J].河南中医,200626(4):6-7.
[12]陈静,张幼明,兰颖.梅花针的临床应用述论[J].湖北中医杂志,2011,33(5):50-51.
[13]黄帝内经素问[M].北京:人民卫生出版社,2012:197.
[14]巩小丽.梅花针叩刺在皮肤病的临床应用[J].甘肃医药,2014,33(6):450-451.
[15]滕秀香,濮凌云.柴松岩“二阳致病”学术思想及临床经验解析[J].中医药信息,2015,32(1):65-66.
[16]巩小丽.梅花针叩刺在皮肤病的临床应用[J].甘肃医药,2014,33(6):450-451.
[17]魏波,江泓成.梅花针面部叩刺治疗重度痤疮100例[J].暨南大学学报(自然科学与医学版),2004,25(2):244-245.
[18]黄敏婷,郑光珊,韦斌,等.梅花针放血对Ⅱ度寻常性痤疮疗效观察[J].广西中医药,2018,41(3):38-39.
[19]张琳,吴凡,薛岚显,等.电梅花针叩刺疗法治疗寻常型痤疮的对照研究[J].时珍国医国药,2014,25(11):2817-2818.