3.0T磁共振扩散加权成像对老年前列腺癌与前列腺增生的鉴别诊断价值
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摘要
目的探究3.0T磁共振扩散加权成像在鉴别诊断老年前列腺癌与老年前列腺增生的应用价值。方法回顾性分析2016年11月至2017年11月如皋市人民医院收治的136例老年前列腺癌及前列腺增生患者的临床资料,根据病理诊断结果将其中病理确诊的68例老年前列腺癌患者设为观察组,将68例老年前列腺增生患者设为对照组。所有患者均行3.0T磁共振扩散加权成像。比较两组患者表观扩散系数(ADC值)、弥散加权成像(DWI)信号强度及增强磁共振成像(DCE-MRI)参数。结果观察组患者ADC值低于对照组,差异有统计学意义(P <0. 05);在扩散敏感因子(b)值=50 s/mm~2及800 s/mm~2时,观察组的DWI信号强度均低于对照组,差异有统计学意义(P <0. 05);观察组DCE-MRI参数(Kep、K trans及Ve)水平均高于对照组,差异有统计学意义(P <0. 05)。结论 3.0T磁共振扩散加权成像能够通过ADC值、DWI信号强度及DCE-MRI参数为鉴别诊断老年前列腺癌与前列腺增生提供参考。
Objective To explore the value of diffusion-weighted 3.0T imaging in differential diagnosis of prostate cancer and benign prostatic hyperplasia in the elderly. Methods The clinical data of 136 elderly patients with prostate cancer and benign prostatic hyperplasia admitted to Rugao People's Hospital of Nantong City from November 2016 to November 2017 were retrospectively analyzed. Sixty-eight patients with pathological diagnosis and elderly patients with prostate cancer were included in observation group,while another 68 elderly patients with benign prostatic hyperplasia as the control group. All patients underwent 3.0T magnetic resonance diffusion-weighted imaging. The apparent diffusion coefficient (ADC value),diffusion-weighted imaging (DWI) signal intensity,and enhanced magnetic resonance imaging (DCE-MRI) parameters were compared between the two groups. Results The ADC value of observation group was lower than that of control group,and the difference was statistically significant (P < 0. 05); when the diffusion sensitivity factor (b) = 50 s/mm~2 and 800 s/mm~2,the DWI signal intensity of observation group was lower than that of control group,and the difference was statistically significant (P < 0. 05); DCE-MRI parameters (Kep,K trans and Ve) and levels of observation group were higher than those of control group,and the difference was statistically significant (P < 0. 05). Conclusion 3.0T MR diffusion-weighted imaging can provide a basis for differential diagnosis of prostate cancer and benign prostatic hyperplasia by ADC value,DWI signal intensity and DCE-MRI parameters.
Objective To explore the value of diffusion-weighted 3.0T imaging in differential diagnosis of prostate cancer and benign prostatic hyperplasia in the elderly. Methods The clinical data of 136 elderly patients with prostate cancer and benign prostatic hyperplasia admitted to Rugao People's Hospital of Nantong City from November 2016 to November 2017 were retrospectively analyzed. Sixty-eight patients with pathological diagnosis and elderly patients with prostate cancer were included in observation group,while another 68 elderly patients with benign prostatic hyperplasia as the control group. All patients underwent 3.0T magnetic resonance diffusion-weighted imaging. The apparent diffusion coefficient (ADC value),diffusion-weighted imaging (DWI) signal intensity,and enhanced magnetic resonance imaging (DCE-MRI) parameters were compared between the two groups. Results The ADC value of observation group was lower than that of control group,and the difference was statistically significant (P < 0. 05); when the diffusion sensitivity factor (b) = 50 s/mm~2 and 800 s/mm~2,the DWI signal intensity of observation group was lower than that of control group,and the difference was statistically significant (P < 0. 05); DCE-MRI parameters (Kep,K trans and Ve) and levels of observation group were higher than those of control group,and the difference was statistically significant (P < 0. 05). Conclusion 3.0T MR diffusion-weighted imaging can provide a basis for differential diagnosis of prostate cancer and benign prostatic hyperplasia by ADC value,DWI signal intensity and DCE-MRI parameters.
引文
[1]陆晶,谭颖.盆腔磁共振EPI扩散加权成像在老年前列腺癌中的诊断价值[J].医疗装备,2018,31(5):54-55.
[2]徐佳佳,王红,闵朋,等.多b值弥散加权成像ADC值对前列腺癌的诊断价值[J].检验医学与临床,2017,14(13):1861-1863.
[3]JIA J B,HOUSHYAR R,VERMA S,et al.Prostate cancer on computed tomography:A direct comparison with multi-parametric magnetic resonance imaging and tissue pathology[J].Eur J Radiol,2016,85(1):261-267.
[4]田野,邵强,宋健,等.北京市多中心社区前列腺增生流行病学调查:BPC-BPH研究结果[J].中华泌尿外科杂志,2010,31(3):164-198.
[5]潘昌远,叶华震,梅淼华,等.磁共振扩散加权成像在老年前列腺癌诊断中的应用价值[J].中国老年学杂志,2016,36(8):1895-1897.
[6]GAZIEV G,WADHWA K,BARRETT T,et al.Defining the learning curve for multiparametric magnetic resonance imaging(MRI)of the prostate using MRI-transrectal ultrasonography(TRUS)fusion-guided transperineal prostate biopsies as a validation tool[J].BJU Int,2016,117(1):80-86.
[7]杨兴胜,李维,李丰华,等.高b值DWI扫描与动态增强磁共振成像在前列腺疾病诊断中的临床价值[J].中国实用医药,2017,12(17):22-24.
[8]梁其洲,李香营,陈建强,等.不同b值磁共振弥散加权成像在鉴别前列腺癌和前列腺增生中的价值[J].中国老年学杂志,2017,37(14):3490-3491.
[9]程丽,徐凯,汪秀玲,等.弥散加权成像及动态增强在前列腺癌诊断中的临床应用价值[J].实用癌症杂志,2017,32(11):1832-1834.
[10]ROMARIC L,OLIVIER C,MORGAN M,et al.Current role of multiparametric magnetic resonance imaging for prostate cancer[J].Quant Imaging Med Surg,2015,5(5):754-764.
[11]王龙江,兰受昌,张国伟,等.3.0T MR动态增强成像在前列腺癌诊断中的应用研究[J].中国CT和MRI杂志,2017,15(5):121-123.
[12]陈翔,朱庆强,叶靖,等.高b值DWI对低PSA水平前列腺癌和前列腺增生伴间质炎的鉴别诊断价值[J].医学影像学杂志,2017,27(10):1974-1977.
[13]TOMASZ S,ANDRZEJ N,FRANTIEK Z,et al.Novel trends in transrectal ultrasound imaging of prostate gland carcinoma[J].J Ultrason,2014,14(58):306-319.
[14]卢方.磁共振扩散加权成像在前列腺癌诊断中应用研究[J].现代医用影像学,2017,26(4):1017-1018.
[2]徐佳佳,王红,闵朋,等.多b值弥散加权成像ADC值对前列腺癌的诊断价值[J].检验医学与临床,2017,14(13):1861-1863.
[3]JIA J B,HOUSHYAR R,VERMA S,et al.Prostate cancer on computed tomography:A direct comparison with multi-parametric magnetic resonance imaging and tissue pathology[J].Eur J Radiol,2016,85(1):261-267.
[4]田野,邵强,宋健,等.北京市多中心社区前列腺增生流行病学调查:BPC-BPH研究结果[J].中华泌尿外科杂志,2010,31(3):164-198.
[5]潘昌远,叶华震,梅淼华,等.磁共振扩散加权成像在老年前列腺癌诊断中的应用价值[J].中国老年学杂志,2016,36(8):1895-1897.
[6]GAZIEV G,WADHWA K,BARRETT T,et al.Defining the learning curve for multiparametric magnetic resonance imaging(MRI)of the prostate using MRI-transrectal ultrasonography(TRUS)fusion-guided transperineal prostate biopsies as a validation tool[J].BJU Int,2016,117(1):80-86.
[7]杨兴胜,李维,李丰华,等.高b值DWI扫描与动态增强磁共振成像在前列腺疾病诊断中的临床价值[J].中国实用医药,2017,12(17):22-24.
[8]梁其洲,李香营,陈建强,等.不同b值磁共振弥散加权成像在鉴别前列腺癌和前列腺增生中的价值[J].中国老年学杂志,2017,37(14):3490-3491.
[9]程丽,徐凯,汪秀玲,等.弥散加权成像及动态增强在前列腺癌诊断中的临床应用价值[J].实用癌症杂志,2017,32(11):1832-1834.
[10]ROMARIC L,OLIVIER C,MORGAN M,et al.Current role of multiparametric magnetic resonance imaging for prostate cancer[J].Quant Imaging Med Surg,2015,5(5):754-764.
[11]王龙江,兰受昌,张国伟,等.3.0T MR动态增强成像在前列腺癌诊断中的应用研究[J].中国CT和MRI杂志,2017,15(5):121-123.
[12]陈翔,朱庆强,叶靖,等.高b值DWI对低PSA水平前列腺癌和前列腺增生伴间质炎的鉴别诊断价值[J].医学影像学杂志,2017,27(10):1974-1977.
[13]TOMASZ S,ANDRZEJ N,FRANTIEK Z,et al.Novel trends in transrectal ultrasound imaging of prostate gland carcinoma[J].J Ultrason,2014,14(58):306-319.
[14]卢方.磁共振扩散加权成像在前列腺癌诊断中应用研究[J].现代医用影像学,2017,26(4):1017-1018.