芍甘定颤汤联合颅底七穴针刺疗法对帕金森病患者影响研究
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摘要
目的:观察芍甘定颤汤联合颅底七穴针刺疗法对帕金森病患者影响。方法:选取我院2015年3月～2016年12月收治的90例帕金森病患者作为研究对象,采取随机双盲法将患者分为观察组与对照组,对照组患者(45例)治疗后常规护理,观察组患者(45例)则在常规干预基础上给予芍甘定颤汤及颅底七穴针刺疗法干预,对比两组患者干预后疗效、干预前后帕金森病功能评定量表(改良UPDRS)评分、患者并发症情况及1年复发率、干预满意率。结果:观察组患者干预后临床治疗总有效率为95. 56%,高于对照组82. 22%,P<0. 05;干预前,两组患者改良UPDRS评分相当(P>0. 05),干预后各组评分均改善,观察组评分改善程度优于对照组,P<0. 01;观察组患者并发症率为2. 22%,低于对照组15. 56%,P <0. 05;观察组患者1年复发率为4. 44%,低于对照组20. 00%,干预满意率为97. 78%,高于对照组80. 00%,P<0. 05,差异具有统计学意义。结论:芍甘定颤汤联合颅底七穴针刺疗法对帕金森病患者具有积极影响,患者临床疗效提升,功能改善,并发症率及复发率降低,患者恢复好,满意率高,可推广应用。
Objective: To explore the effect of Shaogan Dingchan Decoction combined with acupuncture therapy of seven points in skull base for patients with Parkinson' s disease. Methods: Selected from March 2015 to December 2016 were 90cases of Parkinson' s patients as the research object,adopted random double blind method to divide the patients into observation group and controlled group,the controlled group(45cases) was given routine nursing care after treatment,the observation group(45cases) was given Shaogan Dingchan Decoction combined with acupuncture therapy of seven points in skull base on the basis of the controlled group,compared the two groups of patients after the intervention effect,before and after the intervention in Parkinson' s disease rating scale(UPDRS) improved function score,patient satisfaction and complications and the recurrence rate,intervention 1year. Results: The total effective rate of clinical treatment after intervention was 95. 56%,higher than 82. 22% in the controlled group,P<0. 05. Before the intervention,the UPDRS scores of the two groups were comparable(P>0. 05). The scores of each group were improved after the intervention,and the improvement of the observation group was better than that of the controlled group,P<0. 01. The complication rate was 2. 22% in the observation group,and 15. 56% in the controlled group,P<0. 05. In the observation group,the recurrence rate was 4. 44%,lower than the controlled group 20. 00%,and the intervention satisfaction rate was 97. 78%,higher than 80. 00% in the controlled group,P < 0. 05,and the difference was statistically significant. Conclusion: Shaogan Dingchan Decoction combined with acupuncture therapy of seven points in skull base has positive effects on Parkinson' s disease,has certain clinical curative effect,the function has improved,the rate of the complications and the recurrence rate are low,patients recover are well,satisfaction is high,can be applied.
Objective: To explore the effect of Shaogan Dingchan Decoction combined with acupuncture therapy of seven points in skull base for patients with Parkinson' s disease. Methods: Selected from March 2015 to December 2016 were 90cases of Parkinson' s patients as the research object,adopted random double blind method to divide the patients into observation group and controlled group,the controlled group(45cases) was given routine nursing care after treatment,the observation group(45cases) was given Shaogan Dingchan Decoction combined with acupuncture therapy of seven points in skull base on the basis of the controlled group,compared the two groups of patients after the intervention effect,before and after the intervention in Parkinson' s disease rating scale(UPDRS) improved function score,patient satisfaction and complications and the recurrence rate,intervention 1year. Results: The total effective rate of clinical treatment after intervention was 95. 56%,higher than 82. 22% in the controlled group,P<0. 05. Before the intervention,the UPDRS scores of the two groups were comparable(P>0. 05). The scores of each group were improved after the intervention,and the improvement of the observation group was better than that of the controlled group,P<0. 01. The complication rate was 2. 22% in the observation group,and 15. 56% in the controlled group,P<0. 05. In the observation group,the recurrence rate was 4. 44%,lower than the controlled group 20. 00%,and the intervention satisfaction rate was 97. 78%,higher than 80. 00% in the controlled group,P < 0. 05,and the difference was statistically significant. Conclusion: Shaogan Dingchan Decoction combined with acupuncture therapy of seven points in skull base has positive effects on Parkinson' s disease,has certain clinical curative effect,the function has improved,the rate of the complications and the recurrence rate are low,patients recover are well,satisfaction is high,can be applied.
引文
[1]金泽,王玉琳,姜珊珊,等.洋金花对帕金森病大鼠脑纹状体组织SOD、GSH-Px影响的研究[J].中医药信息,2013,30(2):87~90
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[14]刘志红,卢健军,郑文华,等.帕金森病患者采用Synapsys静动态平衡仪进行平衡和步态训练的效果观察[J].护理学报,2016,08(2):48~52
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[16]陈清云,杨冰,杨莉,等.中医特色护理对帕金森病患者生活质量的影响[J].按摩与康复医学,2015,11(14):107~108
[17]刘初容,郑文华,莫昊风,等.董氏奇穴针刺对帕金森病患者步行平衡功能的影响[J].上海针灸杂志,2016,35(10):1187~1189
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[19]黄宁静,李文涛.止颤汤对帕金森病异动症大鼠DARPP-32磷酸化表达的影响[J].中西医结合心脑血管病杂志,2018,16(04):417~420
[2]张改,沈晓明,马云枝,等.马云枝教授从肝辨治帕金森病经验简析[J].中医药学报,2016,44(3):86~88
[3]赵亚明,胡琦.天麻钩藤颗粒联合左旋多巴治疗帕金森病的疗效观察[J].现代药物与临床,2017,32(3):403~406
[4]郎素芝.司来吉兰联合普拉克索治疗帕金森病伴抑郁的疗效观察[J].现代药物与临床,2015,06(8):983~986
[5]梁靖蓉,郭长青,芦娟,等.针刀干预对帕金森病模型大鼠行为学及谷胱甘肽的影响[J].针灸临床杂志,2017,33(3):61~65
[6]尹洪娜,韩超,孙忠人,等.针刺治疗帕金森病随机对照临床研究文献Meta分析[J].针灸临床杂志,2016,32(8):67~70
[7]周海东.头针加电针治疗帕金森病36例[J].四川中医,2004,22(4):88~89
[8]杨松涛,胡晓梅,柴天川,等.震颤停抗帕金森病小鼠肌肉震颤作用的实验研究[J].四川中医,2005,23(7):19~20
[9]吕姣.普拉克索联合左旋多巴治疗帕金森病疗效及安全性研究[J].临床军医杂志,2017,45(1):53~55
[10]陈鹏.丁苯酞治疗帕金森病合并抑郁症的临床效果[J].空军医学杂志,2016,32(5):330~333
[11]黄良海,钱进军,巩企霞,等.帕金森病伴轻度认知障碍与表皮生长因子水平的相关性分析[J].江苏大学学报(医学版),2016,26(3):258~260
[12]邵艳,张兆萍,王慧,等.护理干预对帕金森病患者生活质量和运动功能的影响[J].现代中西医结合杂志,2015,09(15):1686~1687,1688
[13]徐臻,夏进.耳穴埋豆联合心理护理对帕金森病患者焦虑、抑郁的影响[J].按摩与康复医学,2017,8(1):73~74
[14]刘志红,卢健军,郑文华,等.帕金森病患者采用Synapsys静动态平衡仪进行平衡和步态训练的效果观察[J].护理学报,2016,08(2):48~52
[15]蔡月梅,王丽芳,张秋云,等.帕金森患者的认知功能与康复护理效果分析[J].中国伤残医学,2016,07(1):132~133
[16]陈清云,杨冰,杨莉,等.中医特色护理对帕金森病患者生活质量的影响[J].按摩与康复医学,2015,11(14):107~108
[17]刘初容,郑文华,莫昊风,等.董氏奇穴针刺对帕金森病患者步行平衡功能的影响[J].上海针灸杂志,2016,35(10):1187~1189
[18]刘艳慧,陈涛.针刺治疗帕金森病的研究进展[J].国际老年医学杂志,2016,37(5):232~238
[19]黄宁静,李文涛.止颤汤对帕金森病异动症大鼠DARPP-32磷酸化表达的影响[J].中西医结合心脑血管病杂志,2018,16(04):417~420