中药类保健食品增强免疫力功能评价现状和研究策略
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摘要
目前中药类复方保健食品的保健功能评价缺乏中医药理论支持,不能充分体现保健功能的作用特征、量效关系、作用机制,保健食品评价技术规范相对滞后,且已废除。增强免疫功能的中药复方保健食品在已批复的产品中占比最高,已高达30. 33%。该文对中药保健食品增强免疫功能评价现状进行归纳、分析和挖掘,发现目前中药保健食品的评价与其他保健食品的评价未进行区分,缺乏中医药特色。中药保健食品增强免疫力功能的评价不仅缺乏中医理论指导,而且技术手段滞后,缺乏免疫活性物质相关评价的技术手段,免疫细胞评价部分亟待细化完善,限制了中药保健食品行业的发展。因此,中药保健食品的增强免疫功能评价应以中医药养生理论为指导,中医体质辨识为基础,紧密围绕其保健功能声称,结合现代科学技术手段,提出新的评价模式,制订适宜于评价中药保健食品保健功能作用的评价技术和技术规范,从根本上保证中药保健食品产业的健康、有序、快速、持续发展。
At present,the function evaluation of health food containing Chinese materia medica is in lack of theoretical support of Chinese medicine,which can't reflect the function characteristics,dose-effect relationship and mechanism of functional food. What' s more,the evaluation technology of health food containing Chinese materia medica is relatively lagging behind and has been abolished now,which seriously restricts the development of health food containing Chinese materia medica industry. The proportion of health food containing Chinese materia medica with enhancing immune function is the highest among approved products,which is up to 30.33%. By collecting,analyzing and digging the current evaluation situation of enhancing immune function of health food containing Chinese materia medica,this paper has shown that there is no difference between health food containing Chinese materia medica evaluation and other functional food evaluation. What's more,there is a lack of characteristics of traditional Chinese medicine(TCM). The technological means including evaluation of immune active substances is under-developed and the immune cell evaluation needs to be refined and improved urgently,restricting the development of health food containing Chinese materia medica industry. Therefore,the evaluation of the enhanced immune function of health food containing Chinese materia medica should be guided by health-preserving theory in TCM,and based on the identification of TCM constitution for its claim of health function. With TCM theory and modern scientific technological means,a new evaluation model for immune function enhancement of health food containing Chinese materia medica is put forward to distinguish it from other functional food and traditional medicines. Formulation of the evaluation technology and technical specifications suitable for health food containing Chinese materia medica can fundamentally ensure the healthy,orderly,fast and sustainable development of health food containing Chinese materia medica industry.
At present,the function evaluation of health food containing Chinese materia medica is in lack of theoretical support of Chinese medicine,which can't reflect the function characteristics,dose-effect relationship and mechanism of functional food. What' s more,the evaluation technology of health food containing Chinese materia medica is relatively lagging behind and has been abolished now,which seriously restricts the development of health food containing Chinese materia medica industry. The proportion of health food containing Chinese materia medica with enhancing immune function is the highest among approved products,which is up to 30.33%. By collecting,analyzing and digging the current evaluation situation of enhancing immune function of health food containing Chinese materia medica,this paper has shown that there is no difference between health food containing Chinese materia medica evaluation and other functional food evaluation. What's more,there is a lack of characteristics of traditional Chinese medicine(TCM). The technological means including evaluation of immune active substances is under-developed and the immune cell evaluation needs to be refined and improved urgently,restricting the development of health food containing Chinese materia medica industry. Therefore,the evaluation of the enhanced immune function of health food containing Chinese materia medica should be guided by health-preserving theory in TCM,and based on the identification of TCM constitution for its claim of health function. With TCM theory and modern scientific technological means,a new evaluation model for immune function enhancement of health food containing Chinese materia medica is put forward to distinguish it from other functional food and traditional medicines. Formulation of the evaluation technology and technical specifications suitable for health food containing Chinese materia medica can fundamentally ensure the healthy,orderly,fast and sustainable development of health food containing Chinese materia medica industry.
引文
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[2]李虹,张蓉蓉.中药复方治疗白细胞减少症用药规律分析[J].中医杂志,2015,56(4):338.
[3]韩飞,彭珍,周志渝,等.功效性分类中药对提高机体免疫功能的研究进展[J].中草药,2016,47(14):2549.
[4]张翼冠,谭蕊蓉,任思冲,等.基于中药复方适度调节原理与广义免疫组平衡监测的中医证候研究与中药复方药效评价新思路、新方法[J].中国中药杂志,2018,43(16):3229.
[5]关洪全,韩晓伟,梁洪志.试论中医“气血”学说中的免疫学思想[J].中医药导报,2008(1):7.
[6]吕文博,王爽,叶阳.中药免疫增强剂研究进展[J].黑龙江生态工程职业学院学报,2015,28(4):17.
[7]吕小成,张乐帅,王富军.中药多糖的免疫调节作用及研究进展[J].上海中医药大学学报,2016,30(3):97.
[8]刘霜琪,李冰菲,苏慧,等.中药黄芪在保健品中的应用概述[J].黑龙江科技信息,2016(6):75.
[9]陈楠.亚健康的中医体质辨识及健康指导干预效果的研究[J].现代诊断与治疗,2014,25(17):3895.
[10]孙淑英.中医体质辨识对亚健康的分类及健康指导干预的效果探究[J].四川中医,2016,34(12):56.
[11]孙理军,柏云飞.体质辨识在“治未病”中的地位及作用[J].现代中医药,2015,35(6):58.
[12]陈军浩.流式细胞术在临床及科研中的应用[J].临床检验杂志,2012,30(10):861.
[13]齐丽娟,李宁.免疫毒理学的评价方法及其研究进展[J].国外医学·卫生学分册,2008(3):174.
[14]陈朱波.流式细胞术在免疫学中的应用[C].北京:第2届中国免疫学会青年学者论坛,2012.
[15]刘春发,胡建新,屈新辉.中药制剂对免疫功能促进作用的研究进展[J].中国医药导报,2013,10(28):27.
[16]但刚,刘晨霞,吴丽娟. T淋巴细胞功能及检测方法[J].国际检验医学杂志,2015,36(3):377.
[17]刘丹丽,邵喜英,罗奇,等.乳腺癌患者化疗所致发热性中性粒细胞减少症的预防和治疗进展[J].中国肿瘤,2015,24(9):779.