岭南地区近20年肝硬化腹水中医用药规律研究
|
摘要
目的探讨岭南地区近20年肝硬化腹水中医用药规律。方法对1996-2016年岭南地区中医药治疗肝硬化腹水临床资料进行回顾性总结,采用数据挖掘技术,结合中医理论,总结岭南地区现代医家治疗肝硬化腹水的用药规律。结果本研究共纳入84篇论文,方剂89首,药物138味,其中补虚药、利水渗湿药、活血化瘀药、理气药共占74.71%,常用中药20味;药物归经涉及12个脏腑,主要是脾经、肝经、肺经、胃经、肾经、心经为多,共占84.49%;所有药物涉及11种药味,出现的总频次为1 620次,前3位的甘、苦、辛药味共占81.36%,在所有用药中支持度最高的药对是茯苓和白术,置信度最高的药对是茯苓与柴胡。结论肝硬化腹水所用药物功效、药味、归经以及常用药对与肝硬化腹水的病因、病机及所处地域密切相关,这些用药特点及规律可为目前肝硬化腹水的中医辨证论治提供理论依据和临床借鉴。
Objective To explore the regulation of TCM treatment for cirrhosis ascites patients from Lingnan area in recent 20 years.Methods The literature of cirrhosis ascites TCM treatment from Lingnan area in recent 20 years were analyzed and Chinese Medicine Medication of cirrhosis ascites patients was summarized by analyzing the frequency of herbs used in the literature.Results Among the 138 herbs,the herbs of tonifying,removing dampness and promoting diuresis,promoting blood circulation and removing blood stasis,Qi Regulating,totally accounted for 74.71%.The attributive channel of these herbs involved in 12 viscera,in which spleen meridian,liver meridian,lung meridian,gastroenterology meridian,kidney meridian and heart meridian accounted for 84.49%.All herbs involved in 7 kinds of herbal flavors,and total appearance frequency of the 11 flavors was 1620,in which sweetish,bitterness,pungent herbs accounted for 81.36%.Among all the drugs,the highest support degree of paired drugs was Fuling and Baizhu,and the highest confidence of paired drugs was Fuling and Chaihu.Conclusion Efficacy,property flavors and attributive channel of herb medicine used for cirrhosis ascites are closely related to the pathogen and pathogenesis and the patients′region.These herbal medication regularity provides a reference for the current syndrome diferentiation and treatment of cirrhosis ascites.
Objective To explore the regulation of TCM treatment for cirrhosis ascites patients from Lingnan area in recent 20 years.Methods The literature of cirrhosis ascites TCM treatment from Lingnan area in recent 20 years were analyzed and Chinese Medicine Medication of cirrhosis ascites patients was summarized by analyzing the frequency of herbs used in the literature.Results Among the 138 herbs,the herbs of tonifying,removing dampness and promoting diuresis,promoting blood circulation and removing blood stasis,Qi Regulating,totally accounted for 74.71%.The attributive channel of these herbs involved in 12 viscera,in which spleen meridian,liver meridian,lung meridian,gastroenterology meridian,kidney meridian and heart meridian accounted for 84.49%.All herbs involved in 7 kinds of herbal flavors,and total appearance frequency of the 11 flavors was 1620,in which sweetish,bitterness,pungent herbs accounted for 81.36%.Among all the drugs,the highest support degree of paired drugs was Fuling and Baizhu,and the highest confidence of paired drugs was Fuling and Chaihu.Conclusion Efficacy,property flavors and attributive channel of herb medicine used for cirrhosis ascites are closely related to the pathogen and pathogenesis and the patients′region.These herbal medication regularity provides a reference for the current syndrome diferentiation and treatment of cirrhosis ascites.
引文
[1]邓铁涛.岭南医学[J].新中医,1999,(8):9-10.
[2]王伟彪,郑洪.岭南医学研究的历史现状与未来[J].中国医药学报,1998,(2):13-15.
[3]于林童,曲文白,余新波,等.数据挖掘方法在名老中医用药规律研究中的应用现状[J].中医杂志,2017,58(10):886-888.
[2]王伟彪,郑洪.岭南医学研究的历史现状与未来[J].中国医药学报,1998,(2):13-15.
[3]于林童,曲文白,余新波,等.数据挖掘方法在名老中医用药规律研究中的应用现状[J].中医杂志,2017,58(10):886-888.