茵陈蒿汤历代剂量变化规律探讨
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摘要
目的:对古籍中治疗黄疸的名方"茵陈蒿汤"进行剂量考证,为茵陈蒿汤的现代临床应用提供剂量参考依据。方法:以《中华医典》为数据源,以"茵陈蒿汤""茵陈""茵陈蒿""疸""黄疸""黄瘅""谷疸""酒疸""女劳疸""黑疸""发黄""阳黄""阴黄"为检索词,对东汉至清代近两千年的文献进行搜集,检索茵陈蒿汤文献,应用"SPSS19.0"建立数据库,并进行数据分析。结果:茵陈蒿汤中,茵陈、大黄、栀子历代总平均剂量依次为128.93 g、60.93 g、15.12 g。古代医家应用茵陈蒿汤治疗黄疸时最常出现的剂量关联是:茵陈82 g、大黄27 g、栀子14 g,其剂量配比为6∶2∶1。结论:茵陈蒿汤古代应用中,茵陈用量大,建议临床应用茵陈蒿汤时,茵陈、大黄、栀子的剂量比为6∶2∶1。
Objective:To explore the dosage of Yinchenhao Decoction(a famous prescription for jaundice)in ancient literature and provide a dosage reference basis for the modern clinical application of Yinchenhao Decoction. Methods:Taking"Yinchenhao Decoction""Yinchen""Yinchenhao""Jaundice""icterus""yellow jaundice""valley jaundice""wine jaundice""female laodle""black jaundice""Fahuang""Yanghuang"and"Yinhuang"as the data sources,the literatures on Yinchenhao Decoction from the Eastern Han Dynasty to the Qing Dynasty in the past two thousand years were searched at Chinese medical classics SPSS 19.0 was used to establish a database and analysis the data. Results:The total average dose of Artemisia capillaris,rhubarb and gardenia were 128.93 g,60.93 g and 15.12 g respectively. Ancient physicians used Yinchenhao Decoction to treat jaundice,the most common dose correlation was:Artemisia capillaris 82 g,rhubarb 27 g,gardenia 14 g,the dose ratio was 6 ∶ 2 ∶ 1. Conclusion:In the ancient application of Yinchenhao Decoction,Artemisia capillaris was used widely. It is suggested that the dosage ratio of Yinchenhao Decoction to Artemisia capillaris,rhubarb and gardenia should be 6∶2∶1.
Objective:To explore the dosage of Yinchenhao Decoction(a famous prescription for jaundice)in ancient literature and provide a dosage reference basis for the modern clinical application of Yinchenhao Decoction. Methods:Taking"Yinchenhao Decoction""Yinchen""Yinchenhao""Jaundice""icterus""yellow jaundice""valley jaundice""wine jaundice""female laodle""black jaundice""Fahuang""Yanghuang"and"Yinhuang"as the data sources,the literatures on Yinchenhao Decoction from the Eastern Han Dynasty to the Qing Dynasty in the past two thousand years were searched at Chinese medical classics SPSS 19.0 was used to establish a database and analysis the data. Results:The total average dose of Artemisia capillaris,rhubarb and gardenia were 128.93 g,60.93 g and 15.12 g respectively. Ancient physicians used Yinchenhao Decoction to treat jaundice,the most common dose correlation was:Artemisia capillaris 82 g,rhubarb 27 g,gardenia 14 g,the dose ratio was 6 ∶ 2 ∶ 1. Conclusion:In the ancient application of Yinchenhao Decoction,Artemisia capillaris was used widely. It is suggested that the dosage ratio of Yinchenhao Decoction to Artemisia capillaris,rhubarb and gardenia should be 6∶2∶1.
引文
[1]仝小林,穆兰澄,吴义春,等.《伤寒论》方剂中非计量单位药物重量的现代实测研究[J].中医杂志,2009(S1):1-2.
[2]张仲景.伤寒论[M].北京:人民卫生出版社,2005:13,77,80.
[3]张仲景.金匮要略[M].北京:人民卫生出版社,2005:5,59.
[4]佚名.神农本草经[M].顾观光,辑.北京:学苑出版社,2007:85,180,239.
[5]陶弘景.名医别录[M].尚志钧,辑校.北京:人民卫生出版社,1986:52.
[6]浙江省中医管理局《张山雷医集》编委会.张山雷医集(上)[M].北京:人民卫生出版社,1995:232.
[7]王好古.汤液本草[M].北京:人民卫生出版社,1987:139.
[8]周岩.本草思辨录[M].北京:人民卫生出版社,1982:122.
[9]张锡纯.医学衷中参西录[M].石家庄:河北人民出版社,1974:333,452.
[10]国家药典委员会.中华人民共和国药典[M].北京:中国医药科技出版社,2015:24,240,248.
[11]邱仕君.邓铁涛医案与研究[M].北京:人民卫生出版社,2004:40-41.
[12]汪承柏.凉血活血重用赤芍治疗淤胆型肝炎13例报告[J].中医杂志,1983,24(6):30.
[13]朱步先,何绍奇,朱胜华,等,朱良春用药经验集[M].长沙:湖南科学技术出版社,2005:112.
[14]宋佳.经方50味药物在明代13位医家中的用量规律研究[D].北京:北京中医药大学,2011:50.
[15]夏廉博,林乾良.祖国医学与医学气象学[J].上海中医药杂志,1980(4):42-46.
[16]竺可祯.中国五千年来气候变迁的初步研究[J].中国科学,1973(2):168-189.
[17]李睿.历史时期中国竹林分布对气候变化的响应[J].竹子研究汇刊,2002,21(2):68-69.
[18]王绍武.公元1380年以来我国华北气温序列的重建[J].中国科学:B辑,1990(5):553-560.
[19]竺可桢.天道与人道[M].北京:北京出版社,2005:84-99.
[20]杨葛亮,杨学.“小冰河期”促成了温病学说[J].河南中医,29(4):325-326.
[2]张仲景.伤寒论[M].北京:人民卫生出版社,2005:13,77,80.
[3]张仲景.金匮要略[M].北京:人民卫生出版社,2005:5,59.
[4]佚名.神农本草经[M].顾观光,辑.北京:学苑出版社,2007:85,180,239.
[5]陶弘景.名医别录[M].尚志钧,辑校.北京:人民卫生出版社,1986:52.
[6]浙江省中医管理局《张山雷医集》编委会.张山雷医集(上)[M].北京:人民卫生出版社,1995:232.
[7]王好古.汤液本草[M].北京:人民卫生出版社,1987:139.
[8]周岩.本草思辨录[M].北京:人民卫生出版社,1982:122.
[9]张锡纯.医学衷中参西录[M].石家庄:河北人民出版社,1974:333,452.
[10]国家药典委员会.中华人民共和国药典[M].北京:中国医药科技出版社,2015:24,240,248.
[11]邱仕君.邓铁涛医案与研究[M].北京:人民卫生出版社,2004:40-41.
[12]汪承柏.凉血活血重用赤芍治疗淤胆型肝炎13例报告[J].中医杂志,1983,24(6):30.
[13]朱步先,何绍奇,朱胜华,等,朱良春用药经验集[M].长沙:湖南科学技术出版社,2005:112.
[14]宋佳.经方50味药物在明代13位医家中的用量规律研究[D].北京:北京中医药大学,2011:50.
[15]夏廉博,林乾良.祖国医学与医学气象学[J].上海中医药杂志,1980(4):42-46.
[16]竺可祯.中国五千年来气候变迁的初步研究[J].中国科学,1973(2):168-189.
[17]李睿.历史时期中国竹林分布对气候变化的响应[J].竹子研究汇刊,2002,21(2):68-69.
[18]王绍武.公元1380年以来我国华北气温序列的重建[J].中国科学:B辑,1990(5):553-560.
[19]竺可桢.天道与人道[M].北京:北京出版社,2005:84-99.
[20]杨葛亮,杨学.“小冰河期”促成了温病学说[J].河南中医,29(4):325-326.