自拟痰瘀汤治疗糖尿病周围神经病变疗效分析
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摘要
目的:分析探讨自拟痰瘀汤治疗糖尿病周围神经病变的临床疗效。方法:选取2016年6月-2018年6月梅州市第二中医医院及梅州铁炉桥医院门诊、急诊收治的90例糖尿病血管神经病变患者随机分为A、B、C三组,A组给予纯西药治疗,B组给予纯中药治疗,C组给予中西医联合治疗,比较三组患者临床疗效、治疗前后中医症状积分、血糖、血脂指标、神经传导速度。结果:A、B两组患者临床疗效总有效率均显著低于C组(P <0.05),A、B两组疗效差异无统计学意义(P> 0.05),治疗前三组中医症状积分、血糖、血脂指标、神经传导速度差异无统计学意义(P> 0.05),治疗后C组患者中医症状积分、血糖、血脂指标、神经传导速度较A、B两组改善更显著,差异均具有统计学意义(P <0.05)。结论:自拟痰瘀汤治疗糖尿病周围神经病变可显著提高临床疗效,改善患者临床症状,促进血糖、血脂、神经传导速度的改善,建议在临床上推广。
Objective: To analyze clinical efficacy of the Tanyu decoction( 痰 瘀 汤) on diabetic peripheral neuropathy. Methods:90 cases were divided into three groups, the group A was given western medicine; the group B was given TCM therapy; the group C was given the integrative medicine. Results: The total efficiency in the group A and the group B was significantly lower than that in the group C(P<0.05). There were no significant difference in the efficacy between the two groups(P>0.05). After treatment, the scores of TCM symptoms, blood glucose, blood lipids, and nerve conduction velocity in the group C were more significant than those in groups A and B(P<0.05). Conclusion: The Tanyu decoction on diabetic peripheral neuropathy shows a good effect, improve clinical symptoms, blood sugar, blood lipids, nerve conduction velocity, and is worthy of clinical promotion.
Objective: To analyze clinical efficacy of the Tanyu decoction( 痰 瘀 汤) on diabetic peripheral neuropathy. Methods:90 cases were divided into three groups, the group A was given western medicine; the group B was given TCM therapy; the group C was given the integrative medicine. Results: The total efficiency in the group A and the group B was significantly lower than that in the group C(P<0.05). There were no significant difference in the efficacy between the two groups(P>0.05). After treatment, the scores of TCM symptoms, blood glucose, blood lipids, and nerve conduction velocity in the group C were more significant than those in groups A and B(P<0.05). Conclusion: The Tanyu decoction on diabetic peripheral neuropathy shows a good effect, improve clinical symptoms, blood sugar, blood lipids, nerve conduction velocity, and is worthy of clinical promotion.
引文
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[7]王家红,张兰.益气活血化痰法治疗糖尿病周围神经病变的临床观察[J].辽宁医学院学报,2015,8(03):18-20.
[2]李天娥.益气活血通络法联合甲钴胺治疗糖尿病周围神经病变的临床观察[D].武汉:湖北中医药大学,2015.
[3]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中国糖尿病杂志,2014,6(07):447-449.
[4]中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002.
[5]栗明,丁常宏,方芳.糖尿病周围神经病变的中医药治疗进展[J].中医药学报,2013,40(06):133-136.
[6]陈建国.益气活血通络汤治疗糖尿病周围神经病变的临床研究[J].中医中药,2014,6(09):115-116.
[7]王家红,张兰.益气活血化痰法治疗糖尿病周围神经病变的临床观察[J].辽宁医学院学报,2015,8(03):18-20.