盐酸替罗非班联合低分子肝素对急性下肢深静脉血栓的效果及安全性分析
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  • 英文篇名:Efficacy and Safety of Tirofiban Hydrochloride Combined with Low Molecular Weight Heparin in the Treatment of Acute Deep Venous Thrombosis of Lower Extremity
  • 作者:李淑桓
  • 英文作者:LI Shuhuan;Emergency Department, people's Hospital,Dingtao District;
  • 关键词:低分子肝素 ; 盐酸替罗非班 ; 急性下肢深静脉血栓
  • 英文关键词:Low molecular weight heparin;;Tirofiban hydrochloride;;Acute deep venous thrombosis of lower extremity
  • 中文刊名:SZBJ
  • 英文刊名:Biped and Health
  • 机构:菏泽市定陶区人民医院急诊科;
  • 出版日期:2019-04-01
  • 出版单位:双足与保健
  • 年:2019
  • 期:v.28;No.213
  • 语种:中文;
  • 页:SZBJ201907045
  • 页数:2
  • CN:07
  • ISSN:11-3086/R
  • 分类号:96-97
摘要
目的研究治疗急性下肢深静脉血栓应用盐酸替罗非班联合地分析肝素的临床效果及安全性。方法将该院诊治的70例急性下肢深静脉血栓的患者作为该次的观察对象并平均分为两个小组,对照组血栓患者使用单一的低分子肝素进行治疗,观察组血栓患者使用低分子肝素联合盐酸替罗非班进行治疗,比较两组血栓患者的治疗效果。结果对照组血栓患者的治疗有效率为62.9%,观察组血栓患者的治疗有效率为91.4%,两组患者的临床疗效差异有统计学意义(P<0.05)。结论治疗急性下肢深静脉血栓使用盐酸替罗非班联合低分子肝素进行治疗的临床效果显著,具有较高的安全性,是一项值得推广的应用。
        Objective To study the clinical efficacy and safety of tirofiban hydrochloride in the treatment of acute deep venous thrombosis of lower extremity. Methods 70 patients with acute deep venous thrombosis of lower extremity were treated in our hospital and were divided into two groups. The control group was treated with single low molecular weight heparin. Low molecular weight heparin(LMWH) combined with tirofiban hydrochloride was used to treat thrombus patients in the observation group. Results The effective rate of thrombus treatment was 62.9 in the control group and 91.4 in the observation group. The difference of clinical efficacy was statistically significant(P<0.05). Conclusion The clinical effect of tirofiban hydrochloride combined with low molecular weight heparin in the treatment of acute deep vein thrombosis of lower extremity is significant, and it is safe and worthy to be popularized.
引文
[1]胡知峰,殷世武,倪才方,等.超声引导下AngioJet联合置管溶栓顺行治疗急性和亚急性下肢深静脉血栓[J/OL].重庆医学:1-10[2019-02-15].http://kns.cnki.net/kcms/detail/50.1097.r.20190128.1425.027.html.
    [2]梁刚,姜振,陈朴一,等.下腔静脉滤器保护下导管接触性溶栓治疗急性期下肢深静脉血栓形成效果观察[J].山东医药,2019,59(2):79-81.
    [3]李红伟.介入溶栓联合抗凝治疗急性下肢深静脉血栓的临床疗效观察[J].实用医学影像杂志,2018,19(6):546-547.
    [4]邢秀宝.盐酸替罗非班联合低分子肝素对急性下肢深静脉血栓的效果及安全性分析[J].黑龙江医药科学,2018,41(5):72-73.